catalog number :
MBS710449
products full name :
Rabbit anti-human A kinase (PRKA) anchor protein 11 polyclonal Antibody
products short name :
A kinase (PRKA) anchor protein 11
products name syn :
A kinase (PRKA) anchor protein 11; AKAP11; AKAP220; DKFZp781I12161; FLJ11304; KIAA0629; PRKA11
other names :
A kinase (PRKA) anchor protein 11, isoform CRA_a; A-kinase anchor protein 11; A-kinase anchor protein 11; A-kinase anchor protein 220 kDa; a kinase anchor protein 220 kDa; A-kinase anchoring protein, 220kDa; protein kinase A anchoring protein 11; protein kinase A-anchoring protein 11; protein phosphatase 1, regulatory subunit 44; A kinase (PRKA) anchor protein 11; A-kinase anchor protein 220 kDa; AKAP 220; hAKAP220; Protein kinase A-anchoring protein 11; PRKA11
other gene names :
AKAP11; AKAP11; PRKA11; AKAP-11; AKAP220; PPP1R44; AKAP220; KIAA0629; AKAP-11; AKAP 220; hAKAP220; PRKA11
uniprot entry name :
AKA11_HUMAN
reactivity :
Human, Mouse, Rat
purity :
Antigen Affinity Purified
tested application :
ELISA (EIA), Western Blot (WB)
other info1 :
Immunogen: Human AKAP11-Specific
other info2 :
Storage Buffer: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
ncbi acc num :
EAX08676.1
ncbi mol weight :
210,512 Da
ncbi pathways :
G Protein Signaling Pathways (198849)
ncbi summary :
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed at high levels throughout spermatogenesis and in mature sperm. It binds the RI and RII subunits of PKA in testis. It may serve a function in cell cycle control of both somatic cells and germ cells in addition to its putative role in spermatogenesis and sperm function. [provided by RefSeq, Jul 2008]
uniprot summary :
AKAP11: Binds to type II regulatory subunits of protein kinase A and anchors/targets them. Belongs to the AKAP110 family. Protein type: Adaptor/scaffold; Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 13q14.11. Cellular Component: microtubule organizing center; peroxisome. Molecular Function: protein kinase A binding; protein phosphatase 1 binding