product summary
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company name :
MyBioSource
product type :
antibody
product name :
Rabbit anti-human 4-hydroxyphenylpyruvate dioxygenase polyclonal Antibody
catalog :
MBS710403
quantity :
0.05 mL
price :
375 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS710403
products type :
Antibody
products full name :
Rabbit anti-human 4-hydroxyphenylpyruvate dioxygenase polyclonal Antibody
products short name :
4-hydroxyphenylpyruvate dioxygenase
products name syn :
4-hydroxyphenylpyruvate dioxygenase; HPD; 4-HPPD; 4HPPD; GLOD3; PPD
other names :
4-hydroxyphenylpyruvate-dioxygenase; 4-hydroxyphenylpyruvate dioxygenase; 4-hydroxyphenylpyruvate dioxygenase; glyoxalase domain containing 3; 4-hydroxyphenylpyruvic acid oxidase; 4-hydroxyphenylpyruvate dioxygenase; 4-hydroxyphenylpyruvic acid oxidase; 4HPPD; HPD; HPPDase
other gene names :
HPD; HPD; PPD; 4HPPD; GLOD3; 4-HPPD; HPPDASE; PPD; 4HPPD; HPD; HPPDase
uniprot entry name :
HPPD_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse
sequence length :
393
purity :
Antigen Affinity Purified
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
other info1 :
Immunogen: Human HPD
other info2 :
Storage Buffer: PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
ncbi gi num :
3860238
ncbi acc num :
AAC73008.1
ncbi mol weight :
40,497 Da
ncbi pathways :
Metabolic Pathways (132956); Metabolism Pathway (477135); Metabolism Of Amino Acids And Derivatives Pathway (106169); Phenylalanine And Tyrosine Catabolism Pathway (106189); Phenylalanine Metabolism Pathway (82960); Phenylalanine Metabolism Pathway (327); Tyrosine Degradation, Tyrosine = Homogentisate Pathway (522534); Tyrosine Degradation, Tyrosine = Homogentisate Pathway (468237); Tyrosine Metabolism Pathway (82959); Tyrosine Metabolism Pathway (325)
ncbi summary :
The protein encoded by this gene is an enzyme in the catabolic pathway of tyrosine. The encoded protein catalyzes the conversion of 4-hydroxyphenylpyruvate to homogentisate. Defects in this gene are a cause of tyrosinemia type 3 (TYRO3) and hawkinsinuria (HAWK). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]
uniprot summary :
HPD: Key enzyme in the degradation of tyrosine. Defects in HPD are the cause of tyrosinemia type 3 (TYRO3). TYRO3 is an inborn error of metabolism characterized by elevations of tyrosine in the blood and urine, seizures and mild mental retardation. Defects in HPD are a cause of hawkinsinuria (HAWK). HAWK is an inborn error of tyrosine metabolism characterized by failure to thrive, persistent metabolic acidosis, fine and sparse hair, and excretion of the unusual cyclic amino acid metabolite, hawkinsin, in the urine. Belongs to the 4HPPD family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: EC 1.13.11.27; Amino Acid Metabolism - phenylalanine; Amino Acid Metabolism - tyrosine; Oxidoreductase; Cofactor and Vitamin Metabolism - ubiquinone and other terpenoid-quinone biosynthesis. Chromosomal Location of Human Ortholog: 12q24.31. Cellular Component: cytosol. Molecular Function: 4-hydroxyphenylpyruvate dioxygenase activity; metal ion binding. Biological Process: L-phenylalanine catabolic process; tyrosine catabolic process. Disease: Hawkinsinuria; Tyrosinemia, Type Iii
size1 :
0.05 mL
price1 :
375 USD
size2 :
0.15 mL
price2 :
715
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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