catalog number :
MBS710320
products full name :
Rabbit anti-human 1-acylglycerol-3-phosphate O-acyltransferase 6 (lysophosphatidic acid acyltransferase, zeta) polyclonal Antibody
products short name :
1-acylglycerol-3-phosphate O-acyltransferase 6 (lysophosphatidic acid acyltransferase, zeta)
products name syn :
1-acylglycerol-3-phosphate O-acyltransferase 6 (lysophosphatidic acid acyltransferase; zeta); AGPAT6; DKFZp586M1819; LPAAT-zeta; LPAATZ; TSARG7
other names :
1-acylglycerol-3-phosphate O-acyltransferase 6 (lysophosphatidic acid acyltransferase, zeta); Glycerol-3-phosphate acyltransferase 4; glycerol-3-phosphate acyltransferase 6; 1-AGP acyltransferase 6; lysophosphatidic acid acyltransferase zeta; testis spermatogenesis apoptosis-related protein 7; 1-acyl-sn-glycerol-3-phosphate acyltransferase zeta; 1-acylglycerol-3-phosphate O-acyltransferase 6 (lysophosphatidic acid acyltransferase, zeta); 1-acylglycerol-3-phosphate O-acyltransferase 6; 1-acylglycerol-3-phosphate O-acyltransferase 6; 1-AGP acyltransferase 6; 1-AGPAT 6; Acyl-CoA:glycerol-3-phosphate acyltransferase 4; Lysophosphatidic acid acyltransferase zeta; LPAAT-zeta
other gene names :
AGPAT6; AGPAT6; LPAATZ; TSARG7; 1-AGPAT 6; LPAAT-zeta; GPAT4; GPAT4; 1-AGP acyltransferase 6; 1-AGPAT 6; LPAAT-zeta
uniprot entry name :
GPAT4_HUMAN
reactivity :
Human, Mouse, Rat
purity :
Antigen Affinity Purified
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
other info1 :
Immunogen: Human AGPAT6
other info2 :
Storage Buffer: PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
ncbi acc num :
AAH61884.1
ncbi mol weight :
52,071 Da
ncbi pathways :
CDP-diacylglycerol Biosynthesis I Pathway (142255); Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway (160977); Glycerolipid Metabolism Pathway (82986); Glycerolipid Metabolism Pathway (361); Glycerophospholipid Biosynthesis Pathway (645313); Glycerophospholipid Metabolism Pathway (82989); Glycerophospholipid Metabolism Pathway (364); Metabolic Pathways (132956); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976)
ncbi summary :
Lysophosphatidic acid acyltransferases (EC 2.3.1.51) catalyze the conversion of lysophosphatidic acid (LPA) to phosphatidic acid (PA). LPA and PA are involved in signal transduction and lipid biosynthesis.[supplied by OMIM, Apr 2004]
uniprot summary :
AGPAT6: Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipid biosynthesis. Active against both saturated and unsaturated long- chain fatty acyl-CoAs. Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. Protein type: Membrane protein, integral; Lipid Metabolism - glycerophospholipid; Lipid Metabolism - ether lipid; Endoplasmic reticulum; Membrane protein, multi-pass; Transferase; Lipid Metabolism - glycerolipid; EC 2.3.1.15. Chromosomal Location of Human Ortholog: 8p11.21. Cellular Component: endoplasmic reticulum membrane; membrane; endoplasmic reticulum; integral to membrane. Molecular Function: glycerol-3-phosphate O-acyltransferase activity; 1-acylglycerol-3-phosphate O-acyltransferase activity. Biological Process: lactation; acyl-CoA metabolic process; glycerophospholipid biosynthetic process; lipid biosynthetic process; glandular epithelial cell maturation; regulation of multicellular organism growth; triacylglycerol biosynthetic process; cellular lipid metabolic process; fatty acid metabolic process; phospholipid metabolic process; phosphatidylcholine biosynthetic process; phosphatidic acid biosynthetic process; diacylglycerol metabolic process; CDP-diacylglycerol biosynthetic process