product summary
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company name :
MyBioSource
product type :
antibody
product name :
Rabbit anti-human scinderin polyclonal Antibody
catalog :
MBS710295
quantity :
0.05 mL
price :
375 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS710295
products type :
Antibody
products full name :
Rabbit anti-human scinderin polyclonal Antibody
products short name :
scinderin
products name syn :
scinderin; SCIN; KIAA1905
other names :
scinderin; Adseverin; adseverin; scinderin; Scinderin
other gene names :
SCIN; SCIN; KIAA1905
uniprot entry name :
ADSV_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
715
purity :
Antigen Affinity Purified
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
other info1 :
Immunogen: Human SCIN
other info2 :
Storage Buffer: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
ncbi gi num :
14331131
ncbi acc num :
AAK60494.1
ncbi mol weight :
52,814 Da
ncbi pathways :
Endochondral Ossification Pathway (198812); Fc Gamma R-mediated Phagocytosis Pathway (114228); Fc Gamma R-mediated Phagocytosis Pathway (106590); Regulation Of Actin Cytoskeleton Pathway (83089); Regulation Of Actin Cytoskeleton Pathway (500); Viral Carcinogenesis Pathway (658418); Viral Carcinogenesis Pathway (662842)
ncbi summary :
SCIN is a Ca(2+)-dependent actin-severing and -capping protein (Zunino et al., 2001 [PubMed 11568009]).[supplied by OMIM, May 2010]
uniprot summary :
SCIN: Ca(2+)-dependent actin filament-severing protein that is presumed to have a regulatory function in exocytosis by affecting the organization of the microfilament network underneath the plasma membrane. In vitro, also has barbed end capping and nucleating activities in the presence of Ca(2+). Regulates chondrocyte proliferation and differentiation. MAP kinases p38 and ERK1/2 mediate the adseverin-induced accelerated differentiation of non-hypertrophic chondrocytes. Belongs to the villin/gelsolin family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 7p21.3. Cellular Component: cytoskeleton; protein complex; cytoplasm; cell cortex. Molecular Function: actin filament binding; phosphatidylinositol-4,5-bisphosphate binding; phosphatidylserine binding; calcium ion binding; actin binding; phosphatidylinositol binding. Biological Process: negative regulation of cell proliferation; actin filament severing; positive regulation of apoptosis; actin filament capping; positive regulation of secretion; positive regulation of megakaryocyte differentiation; regulation of chondrocyte differentiation; actin nucleation; calcium ion-dependent exocytosis
size1 :
0.05 mL
price1 :
375 USD
size2 :
0.15 mL
price2 :
715
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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