product summary
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company name :
MyBioSource
product type :
antibody
product name :
Rabbit anti-human integrin, alpha X (complement component 3 receptor 4 subunit) polyclonal Antibody
catalog :
MBS710275
quantity :
0.05 mL
price :
375 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunocytochemistry, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS710275
products type :
Antibody
products full name :
Rabbit anti-human integrin, alpha X (complement component 3 receptor 4 subunit) polyclonal Antibody
products short name :
integrin, alpha X
products name syn :
integrin; alpha X (complement component 3 receptor 4 subunit); ITGAX; CD11C; SLEB6
other names :
integrin, alpha X (complement component 3 receptor 4 subunit), isoform CRA_b; Integrin alpha-X; integrin alpha-X; leu M5, alpha subunit; p150 95 integrin alpha chain; CD11 antigen-like family member C; leukocyte adhesion receptor p150,95; myeloid membrane antigen, alpha subunit; leukocyte surface antigen p150,95, alpha subunit; leukocyte adhesion glycoprotein p150,95 alpha chain; integrin, alpha X (antigen CD11C (p150), alpha polypeptide); integrin, alpha X (complement component 3 receptor 4 subunit); CD11 antigen-like family member C; Leu M5; Leukocyte adhesion glycoprotein p150,95 alpha chain; Leukocyte adhesion receptor p150,95; CD_antigen: CD11c
other gene names :
ITGAX; ITGAX; CD11C; SLEB6; CD11C
uniprot entry name :
ITAX_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human,Mouse,Rat; Other species are not tested. Please decide the specificity by homology.
sequence length :
719
purity :
Antigen Affinity Purified
form :
Liquid
storage stability :
Shipped at 4 Degree C Upon delivery aliquot and store at -20 Degree C or -80 Degree C. Avoid repeated freeze.
tested application :
ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)
app notes :
ELISA:Use at an assay dependent dilution. WB : 1:200-1:2000. IHC : 1:20-1:200 (Recommender dilutions). Positive WB detected in: Human blood tissue . Positive IHC detected in: Human spleen tissue
other info1 :
Immunogen: Human ITGAX. Conjugate : Non-conjugated
other info2 :
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
products description :
Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis.
ncbi gi num :
119572526
ncbi acc num :
EAW52141.1
ncbi mol weight :
127,829 Da
ncbi pathways :
Cell Surface Interactions At The Vascular Wall Pathway (106062); ECM Proteoglycans Pathway (833812); Extracellular Matrix Organization Pathway (576262); Focal Adhesion Pathway (198795); Hemostasis Pathway (106028); Integrin Cell Surface Interactions Pathway (106110); Integrin-mediated Cell Adhesion Pathway (198816); Regulation Of Actin Cytoskeleton Pathway (83089); Regulation Of Actin Cytoskeleton Pathway (500); Tuberculosis Pathway (213780)
ncbi summary :
This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]
uniprot summary :
ITGAX: Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis. Belongs to the integrin alpha chain family. Protein type: Motility/polarity/chemotaxis; Membrane protein, integral. Chromosomal Location of Human Ortholog: 16p11.2. Cellular Component: cell surface; membrane; plasma membrane; integrin complex. Molecular Function: protein binding; metal ion binding; receptor activity. Biological Process: integrin-mediated signaling pathway; heterotypic cell-cell adhesion; organ morphogenesis; extracellular matrix organization and biogenesis; cell adhesion; blood coagulation; leukocyte migration. Disease: Systemic Lupus Erythematosus
size1 :
0.05 mL
price1 :
375 USD
size2 :
0.15 mL
price2 :
715
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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