catalog number :
MBS710256
products full name :
Rabbit anti-human coagulation factor II (thrombin) receptor-like 1 polyclonal Antibody
products short name :
coagulation factor II (thrombin) receptor-like 1
products name syn :
coagulation factor II (thrombin) receptor-like 1; F2RL1; GPR11; PAR2
other names :
Coagulation factor II (thrombin) receptor-like 1; Proteinase-activated receptor 2; proteinase-activated receptor 2; thrombin receptor-like 1; G-protein coupled receptor 11; protease-activated receptor 2; coagulation factor II receptor-like 1; coagulation factor II (thrombin) receptor-like 1; Coagulation factor II receptor-like 1; G-protein coupled receptor 11; Thrombin receptor-like 1Cleaved into the following 2 chains:Proteinase-activated receptor 2, alternate cleaved 1; Proteinase-activated receptor 2, alternate cleaved 2
other gene names :
F2RL1; F2RL1; PAR2; GPR11; GPR11; PAR2; PAR-2
uniprot entry name :
PAR2_HUMAN
reactivity :
Human, Mouse, Rat
purity :
Antigen Affinity Purified
tested application :
ELISA (EIA), Western Blot (WB)
other info1 :
Immunogen: Human F2RL1
other info2 :
Storage Buffer: PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
ncbi acc num :
AAH18130.1
ncbi mol weight :
44,126 Da
ncbi pathways :
African Trypanosomiasis Pathway 194384!!African Trypanosomiasis Pathway 194323!!Class A/1 (Rhodopsin-like Receptors) Pathway 106357!!G Alpha (q) Signalling Events Pathway 106043!!GPCR Downstream Signaling Pathway 119548!!GPCR Ligand Binding Pathway 161020!!GPCRs, Class A Rhodopsin-like Pathway 198886!!Gastrin-CREB Signalling Pathway Via PKC And MAPK 645295!!Inflammatory Mediator Regulation Of TRP Channels Pathway 948277!!Inflammatory Mediator Regulation Of TRP Channels Pathway 948307
ncbi summary :
Coagulation factor II (thrombin) receptor-like 1 (F2RL1) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL1 is also a member of the protease-activated receptor family. It is activated by trypsin, but not by thrombin. It is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. The F2RL1 gene contains two exons and is widely expressed in human tissues. The predicted protein sequence is 83% identical to the mouse receptor sequence. [provided by RefSeq, Jul 2008]