catalog number :
MBS710201
products full name :
Rabbit anti-human nudE nuclear distribution gene E homolog 1 (A. nidulans) polyclonal Antibody
products short name :
nudE nuclear distribution gene E homolog 1 (A. nidulans)
products name syn :
nudE nuclear distribution gene E homolog 1 (A. nidulans); NDE1; FLJ20101; HOM-TES-87; NUDE; NUDE1
other names :
NudE nuclear distribution gene E homolog 1 (A. nidulans); Nuclear distribution protein nudE homolog 1; nuclear distribution protein nudE homolog 1; nudE nuclear distribution E homolog 1; nudE nuclear distribution gene E homolog 1; LIS1-interacting protein NUDE1, rat homolog; nudE neurodevelopment protein 1
other gene names :
NDE1; NDE1; NDE; LIS4; MHAC; NUDE; NUDE1; HOM-TES-87; NUDE; NudE
uniprot entry name :
NDE1_HUMAN
reactivity :
Human, Mouse, Rat
purity :
Antigen Affinity Purified
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
other info1 :
Immunogen: Human NDE1
other info2 :
Storage Buffer: PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
ncbi acc num :
AAH01421.1
ncbi mol weight :
37,721 Da
ncbi pathways :
Cell Cycle Pathway 530733!!Cell Cycle, Mitotic Pathway 105765!!Centrosome Maturation Pathway 105807!!G2/M Transition Pathway 105801!!Loss Of Nlp From Mitotic Centrosomes Pathway 105811!!Loss Of Proteins Required For Interphase Microtubule Organization From The Centrosome Pathway 105810!!M Phase Pathway 105812!!Mitotic Anaphase Pathway 105818!!Mitotic G2-G2/M Phases Pathway 160942!!Mitotic Metaphase And Anaphase Pathway 730317
ncbi summary :
This gene encodes a member of the nuclear distribution E (NudE) family of proteins. The encoded protein is localized at the centrosome and interacts with other centrosome components as part of a multiprotein complex that regulates dynein function. This protein plays an essential role in microtubule organization, mitosis and neuronal migration. Mutations in this gene cause lissencephaly 4, a disorder characterized by lissencephaly, severe brain atrophy, microcephaly, and severe mental retardation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012]