product summary
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company name :
MyBioSource
product type :
antibody
product name :
Rabbit anti-human minichromosome maintenance complex component 2 polyclonal Antibody
catalog :
MBS710177
quantity :
0.05 mL
price :
375 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS710177
products type :
Antibody
products full name :
Rabbit anti-human minichromosome maintenance complex component 2 polyclonal Antibody
products short name :
minichromosome maintenance complex component 2
products name syn :
minichromosome maintenance complex component 2; MCM2; BM28; CCNL1; CDCL1; D3S3194; KIAA0030; MGC10606; MITOTIN; cdc19
other names :
Minichromosome maintenance complex component 2; DNA replication licensing factor MCM2; DNA replication licensing factor MCM2; cyclin-like 1; nuclear protein BM28; cell devision cycle-like 1; minichromosome maintenance protein 2 homolog; minichromosome maintenance deficient 2 (mitotin); MCM2 minichromosome maintenance deficient 2, mitotin; minichromosome maintenance complex component 2; Minichromosome maintenance protein 2 homolog; Nuclear protein BM28
other gene names :
MCM2; MCM2; BM28; CCNL1; CDCL1; cdc19; D3S3194; MITOTIN; BM28; CCNL1; CDCL1; KIAA0030
uniprot entry name :
MCM2_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
904
purity :
Antigen Affinity Purified
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
other info1 :
Immunogen: Human MCM2
other info2 :
Storage Buffer: PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
ncbi gi num :
127796089
ncbi acc num :
AAH06165.3
ncbi mol weight :
101,896 Da
ncbi pathways :
Activation Of ATR In Response To Replication Stress Pathway (105754); Activation Of The Pre-replicative Complex Pathway (105777); Assembly Of The Pre-replicative Complex Pathway (105821); Cell Cycle Pathway (530733); Cell Cycle Checkpoints Pathway (105739); Cell Cycle, Mitotic Pathway (105765); Cell Cycle Pathway (198811); Cell Cycle Pathway (83054); Cell Cycle Pathway (463); DNA Replication Pathway (198771)
ncbi summary :
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Oct 2012]
uniprot summary :
MCM2: a mini-chromosome maintenance protein, essential for the initiation of eukaryotic genome replication. Allows DNA to undergo a single round of replication per cell cycle. Required for the entry in S phase and for cell division. Protein type: DNA-binding; EC 3.6.4.12. Chromosomal Location of Human Ortholog: 3q21. Cellular Component: nucleoplasm; microtubule cytoskeleton; MCM complex; cytoplasm; nuclear origin of replication recognition complex; nucleus; chromatin. Molecular Function: DNA helicase activity; protein binding; DNA binding; histone binding; metal ion binding; DNA replication origin binding; ATP binding. Biological Process: DNA unwinding during replication; nucleosome assembly; DNA replication initiation; DNA strand elongation during DNA replication; mitotic cell cycle; DNA replication; cell cycle; G1/S transition of mitotic cell cycle
size1 :
0.05 mL
price1 :
375 USD
size2 :
0.15 mL
price2 :
715
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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