catalog number :
MBS710033
products full name :
Rabbit anti-human hemopoietic cell kinase polyclonal Antibody
products short name :
hemopoietic cell kinase
products name syn :
hemopoietic cell kinase; HCK; JTK9
other names :
Hemopoietic cell kinase; Tyrosine-protein kinase HCK; tyrosine-protein kinase HCK; p59-HCK/p60-HCK; hemopoietic cell kinase; hematopoietic cell kinase; HCK proto-oncogene, Src family tyrosine kinase; Hematopoietic cell kinase; Hemopoietic cell kinase; p59-HCK/p60-HCK; p59Hck; p61Hck
other gene names :
HCK; HCK; JTK9; p59Hck; p61Hck
uniprot entry name :
HCK_HUMAN
reactivity :
Human, Mouse, Rat
purity :
Antigen Affinity Purified
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
other info1 :
Immunogen: Human HCK
other info2 :
Storage Buffer: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
ncbi acc num :
AAI08932.2
ncbi mol weight :
59,529 Da
ncbi pathways :
Alpha-synuclein Signaling Pathway 137913!!B Cell Receptor Signaling Pathway 198909!!CXCR4-mediated Signaling Events Pathway 137910!!Chemokine Signaling Pathway 99051!!Chemokine Signaling Pathway 96864!!Class I PI3K Signaling Events Pathway 138022!!Cytokine Signaling In Immune System Pathway 366171!!Disease Pathway 530764!!EPHA Forward Signaling Pathway 138041!!Ephrin B Reverse Signaling Pathway 138052
ncbi summary :
The protein encoded by this gene is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Multiple isoforms with different subcellular distributions are produced due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) codon. [provided by RefSeq, Feb 2010]