catalog number :
MBS710018
products full name :
Rabbit anti-human baculoviral IAP repeat-containing 3 polyclonal Antibody
products short name :
baculoviral IAP repeat-containing 3
products name syn :
baculoviral IAP repeat-containing 3; BIRC3; AIP1; API2; CIAP2; HAIP1; HIAP1; MALT2; MIHC; RNF49
other names :
baculoviral IAP repeat-containing protein 3; Baculoviral IAP repeat-containing protein 3; baculoviral IAP repeat-containing protein 3; IAP-1; IAP homolog C; apoptosis inhibitor 2; RING finger protein 49; mammalian IAP homolog C; inhibitor of apoptosis protein 1; baculoviral IAP repeat-containing 3; TNFR2-TRAF signaling complex protein; TNFR2-TRAF-signaling complex protein 1; baculoviral IAP repeat containing 3; Apoptosis inhibitor 2; API2; C-IAP2; IAP homolog C; Inhibitor of apoptosis protein 1; IAP-1; hIAP-1; hIAP1; RING finger protein 49; TNFR2-TRAF-signaling complex protein 1
other gene names :
BIRC3; BIRC3; AIP1; API2; MIHC; CIAP2; HAIP1; HIAP1; MALT2; RNF49; c-IAP2; API2; IAP1; MIHC; RNF49; API2; IAP-1; hIAP-1; hIAP1
uniprot entry name :
BIRC3_HUMAN
reactivity :
Human, Mouse, Rat
purity :
Antigen Affinity Purified
tested application :
ELISA (EIA), Immunohistochemistry (IHC)
other info1 :
Immunogen: Human BIRC3
other info2 :
Storage Buffer: PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
ncbi acc num :
NP_892007.1
ncbi gb acc num :
NM_182962.2
ncbi mol weight :
68,372 Da
ncbi pathways :
Activated TLR4 Signalling Pathway 106400!!Apoptosis Pathway 198797!!Apoptosis Pathway 83060!!Apoptosis Pathway 470!!Apoptosis Modulation And Signaling Pathway 198822!!C-MYB Transcription Factor Network Pathway 138073!!CD40/CD40L Signaling Pathway 138061!!Caspase Cascade In Apoptosis Pathway 137974!!Ceramide Signaling Pathway 138023!!FAS (CD95) Signaling Pathway 138081
ncbi summary :
This gene encodes a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. It contains 3 baculovirus IAP repeats and a ring finger domain. Transcript variants encoding the same isoform have been identified. [provided by RefSeq, Aug 2011]