catalog number :
MBS7074427
products type :
Recombinant Protein
products full name :
Recombinant Human Dihydropyrimidinase-related protein 1 (CRMP1)
products short name :
[Dihydropyrimidinase-related protein 1 (CRMP1)]
products name syn :
[Collapsin response mediator protein 1]
other names :
[dihydropyrimidinase-related protein 1 isoform 1; Dihydropyrimidinase-related protein 1; dihydropyrimidinase-related protein 1; collapsin response mediator protein 1; Collapsin response mediator protein 1; CRMP-1; Unc-33-like phosphoprotein 3; ULIP-3]
products gene name syn :
[CRMP1]
other gene names :
[CRMP1; CRMP1; DRP1; DRP-1; CRMP-1; DPYSL1; ULIP-3; DPYSL1; ULIP3; DRP-1; CRMP-1; ULIP-3]
sequence positions :
[1-572. Full length.]
sequence :
MSYQGKKSIPHITSDRLLIKGGRIINDDQSLYADVYLED
GLIKQIGENLIVPGGVKTIEANGRMVIPGGIDVNTYLQK
PSQGMTAADDFFQGTRAALVGGTTMIIDHVVPEPGSSLL
TSFEKWHEAADTKSCCDYSLHVDITSWYDGVREELEVLV
QDKGVNSFQVYMAYKDVYQMSDSQLYEAFTFLKGLGAVI
LVHAENGDLIAQEQKRILEMGITGPEGHALSRPEELEAE
AVFRAITIAGRINCPVYITKVMSKSAADIIALARKKGPL
VFGEPIAASLGTDGTHYWSKNWAKAAAFVTSPPLSPDPT
TPDYLTSLLACGDLQVTGSGHCPYSTAQKAVGKDNFTLI
PEGVNGIEERMTVVWDKAVATGKMDENQFVAVTSTNAAK
IFNLYPRKGRIAVGSDADVVIWDPDKLKTITAKSHKSAV
EYNIFEGMECHGSPLVVISQGKIVFEDGNINVNKGMGRF
IPRKAFPEHLYQRVKIRNKVFGLQGVSRGMYDGPVYEVP
ATPKYATPAPSAKSSPSKHQPPPIRNLHQSNFSLSGAQI
DDNNPRRTGHRIVAPPGGRSNITSLG
form :
Liquid containing glycerol. Please note this is Tag Free (No-Tagged). Please disregard the tag information specified below.
storage stability :
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
image1 heading :
SDS-PAGE
other info1 :
Species: Homo sapiens (Human)
other info2 :
Production Note: Special Offer: The E Coli host-expressed protein is manufactured from a stock plasmid containing the protein gene. E Colihost-expressed protein is stocked in different unit sizes ranging from as small as 10 ug to as large as 1 mg. Bulk inventory is also available. The E Coli host-expressed protein has been ordered over and over again by researchers and has stood the test of time as both a robust protein and important target for the research community. It is part of our new program to make our most popular protein targets and corresponding hosts available in expanded unit sizes and with a quick processing time. Select E Coli host-expressed protein for the fastest delivery among all hosts. Please contact our technical support team or email to support@mybiosource.com for more details.
products categories :
Neuroscience
products description :
Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. May participate in cytokinesis.
products references :
Long form collapsin response mediator protein-1 (LCRMP-1) expression is associated with clinical outcome and lymph node metastasis in non-small cell lung cancer patients." Pan S.-H., Chao Y.-C., Chen H.Y., Hung P.F., Lin P.Y., Lin C.W., Chang Y.L., Wu C.T., Lee Y.C., Yang S.-C., Hong T.-M., Yang P.-C. Lung Cancer 67:93-100(2010)
ncbi acc num :
NP_001014809.1
ncbi gb acc num :
NM_001014809.2
ncbi mol weight :
62.2kDa
ncbi pathways :
Axon Guidance Pathway (105688); CRMPs In Sema3A Signaling Pathway (119525); Developmental Biology Pathway (477129); Semaphorin Interactions Pathway (119519)
ncbi summary :
This gene encodes a member of a family of cytosolic phosphoproteins expressed exclusively in the nervous system. The encoded protein is thought to be a part of the semaphorin signal transduction pathway implicated in semaphorin-induced growth cone collapse during neural development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
uniprot summary :
Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. May participate in cytokinesis.