catalog number :
MBS706500
products type :
ELISA Kit
products full name :
Mouse Interleukin-36 beta, IL1F8 ELISA Kit
products short name :
[interleukin 1 family, member 8 (eta)]
products name syn :
[Mouse Interleukin-36 beta (IL1F8) ELISA kit; FIL1; FIL1- (ETA); FIL1H; IL-1F8; IL-1H2; IL1-ETA; IL1H2; MGC126880; MGC126882; IL-1F8 (FIL1-eta) ; IL1F8 (Canonical product IL-1F8a) ; Interleukin-1 Superfamily e; family of interleukin 1-eta; interleukin; interleukin 1 family; member 8 (eta)]
other names :
[interleukin-36 beta isoform 1; Interleukin-36 beta; interleukin-36 beta; FIL1 eta; IL-1 eta; IL-1F8 (FIL1-eta); interleukin-1 eta; interleukin 1, eta; interleukin-1 homolog 2; Interleukin-1 Superfamily e; family of interleukin 1-eta; interleukin-1 family member 8; IL1F8 (Canonical product IL-1F8a); interleukin 1 family, member 8 (eta); interleukin 36, beta; FIL1 eta; Interleukin-1 eta; IL-1 eta; Interleukin-1 family member 8; IL-1F8; Interleukin-1 homolog 2; IL-1H2]
products gene name :
[IL1F8]
other gene names :
[IL36B; IL36B; FIL1; FIL1H; IL1F8; IL1H2; IL-1F8; IL-1H2; IL1-ETA; FIL1-(ETA); FILI-(ETA); IL1F8; IL1H2; IL-1 eta; IL-1F8; IL-1H2]
uniprot entry name :
IL36B_HUMAN
specificity :
This assay has high sensitivity and excellent specificity for detection of rabbit IL-17. No significant cross-reactivity or interference between rabbit IL-17 and analogues was observed.
storage stability :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
other info1 :
Samples: Serum, Plasma, Tissue Homogenates. Assay Type: Quantitative Sandwich. Detection Range: 31.25 pg/ml-2000 pg/ml. Sensitivity: 7.81 pg/ml.
other info2 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
products description :
Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for IL-17 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any IL-17 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for IL-17 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of IL-17 bound in the initial step. The color development is stopped and the intensity of the color is measured.
ncbi acc num :
NP_055253.2
ncbi gb acc num :
NM_014438.4
ncbi mol weight :
18,522 Da
ncbi pathways :
Focal Adhesion Pathway (83067); Focal Adhesion Pathway (478); MAPK Signaling Pathway (83048); MAPK Signaling Pathway (456); Salmonella Infection Pathway (375172); Salmonella Infection Pathway (375149)
ncbi summary :
The protein encoded by this gene is a member of the interleukin 1 cytokine family. Protein structure modeling indicated that this cytokine may contain a 12-stranded beta-trefoil structure that is conserved between IL1A (IL-A alpha) and IL1B (IL-1 beta). This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Two alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
uniprot summary :
Function: Stimulates production of interleukin-6 and interleukin-8 in synovial fibrobasts, articular chondrocytes and mature adipocytes. Induces expression of a number of antimicrobial peptides including beta-defensins 4 and 103 as well as a number of matrix metalloproteases.3 PublicationsManual assertion based on experiment in:Ref.8
size1 :
24-Strip-Wells (LIMIT 1)
size5 :
10x96-Strip-Wells