product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Human adrenomedullin 2, ADM2 ELISA Kit
catalog :
MBS706499
quantity :
48-Strip-Wells
price :
565 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS706499
products type :
ELISA Kit
products full name :
Human adrenomedullin 2, ADM2 ELISA Kit
products short name :
adrenomedullin 2
products name syn :
Human adrenomedullin 2 (ADM2) ELISA kit; RP4-579N16.10; AM2; FLJ21135; dJ579N16.4; OTTHUMP00000196596; intermedin; adrenomedullin 2
other names :
ADM2 preproprotein; ADM2; ADM2; intermedin; adrenomedullin 2; IntermedinCleaved into the following 2 chains:Adrenomedullin-2; AM2Alternative name(s):Intermedin-long; IMDL
products gene name :
ADM2
other gene names :
ADM2; ADM2; AM2; dJ579N16.4; AM2; AM2; IMDL; IMDS
uniprot entry name :
ADM2_HUMAN
reactivity :
Human
sequence length :
148
specificity :
This assay has high sensitivity and excellent specificity for detection of human ADM2. No significant cross-reactivity or interference between human ADM2 and analogues was observed.
storage stability :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
other info1 :
Samples: Serum, plasma, cell culture supernates. Assay Type: Sandwich. Detection Range: 31.25 pg/ml -2000 pg/ml. Sensitivity: The minimum detectable dose of human ADM2 is typically less than 7.8 pg/ml.The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations.
other info2 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
products description :
Principle of the assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for ADM2 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any ADM2 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for ADM2 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of ADM2 bound in the initial step. The color development is stopped and the intensity of the color is measured.
ncbi gi num :
359718926
ncbi acc num :
NP_001240774.1
ncbi gb acc num :
NM_001253845.1
uniprot acc num :
Q7Z4H4
ncbi mol weight :
15,865 Da
ncbi pathways :
Calcitonin-like Ligand Receptors Pathway (106379); Class B/2 (Secretin Family Receptors) Pathway (106378); G Alpha (s) Signalling Events Pathway (119549); GPCR Downstream Signaling Pathway (119548); GPCR Ligand Binding Pathway (161020); Signal Transduction Pathway (477114); Signaling By GPCR Pathway (106356)
ncbi summary :
This gene encodes a protein which is a member of the calcitonin-related hormones. The encoded protein is involved in maintaining homeostasis in many tissues, acting via CRLR/RAMP receptor (calcitonin receptor-like receptor/receptor activity-modifying protein) complexes. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Dec 2011]
uniprot summary :
Function: IMDL and IMDS may play a role as physiological regulators of gastrointestinal, cardiovascular bioactivities mediated by the CALCRL/RAMPs receptor complexes. Activates the cAMP-dependent pathway.1 PublicationManual assertion based on experiment in:Ref.1
size1 :
48-Strip-Wells
price1 :
565 USD
size2 :
96-Strip-Wells
price2 :
810
size3 :
5x96-Strip-Wells
price3 :
2750
size4 :
10x96-Strip-Wells
price4 :
5150
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

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