catalog number :
MBS706291
products type :
ELISA Kit
products full name :
Rat Alpha-synuclein, SNCA ELISA Kit
products short name :
synuclein, alpha (non A4 component of amyloid precursor)
products name syn :
Rat Alpha-synuclein (SNCA) ELISA kit; MGC110988; NACP; PARK1; PARK4; PD1; OTTHUMP00000161559; OTTHUMP00000161561; alpha-synuclein; alpha-synuclein; isoform NACP140; non A-beta component of AD amyloid; synuclein; alpha (non A4 component of amyloid precursor)
other names :
alpha-synuclein; Alpha-synuclein; alpha-synuclein; synuclein, alpha (non A4 component of amyloid precursor)
products gene name :
SNCA
other gene names :
Snca; Snca
uniprot entry name :
SYUA_RAT
specificity :
This assay has high sensitivity and excellent specificity for detection of Rat SNCA. No significant cross-reactivity or interference between Rat SNCA and analogues was observed.
storage stability :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
other info1 :
Samples: Serum, plasma, tissue homogenates. Assay Type: Sandwich. Detection Range: 0.625 ng/ml-40 ng/ml. Sensitivity: 0.156 ng/ml
other info2 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV% is less than 8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV% is less than 10%. Three samples of known concentration were tested in twenty assays to assess. Detection Wavelength: 450 nm. Sample Volume: 50-100ul
products description :
Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for SNCA has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any SNCA present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for SNCA is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of SNCA bound in the initial step. The color development is stopped and the intensity of the color is measured.
ncbi acc num :
NP_062042.1
ncbi gb acc num :
NM_019169.2
ncbi mol weight :
14,515 Da
ncbi pathways :
Alzheimer's Disease Pathway (83489); Alzheimer's Disease Pathway (509); Amyloids Pathway (1010489); Disease Pathway (1010484); EGFR1 Signaling Pathway (198427); Parkinson's Disease Pathway (83490)
ncbi summary :
may play a role in regulation of synaptic vesicle biogenesis and organization; may be involved in neurotransmission [RGD, Feb 2006]
uniprot summary :
Function: May be involved in the regulation of dopamine release and transport.
size4 :
10x96-Strip-Wells