Human Insulin-like growth factor-binding protein 7, IGFBP7/MAC25/PSF ELISA Kit | MyBioSource MBS706238 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human Insulin-like growth factor-binding protein 7, IGFBP7/MAC25/PSF ELISA Kit

catalog :

MBS706238

quantity :

48-Strip-Wells

price :

565 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS706238

products type :

ELISA Kit

products full name :

Human Insulin-like growth factor-binding protein 7, IGFBP7/MAC25/PSF ELISA Kit

products short name :

insulin-like growth factor binding protein 7

products name syn :

Human Insulin-like growth factor-binding protein 7 (IGFBP7/MAC25/PSF) ELISA kit; FSTL2; IGFBP-7; IGFBP-7v; IGFBPRP1; MAC25; PSF; ; insulin-like growth factor binding protein 7

other names :

insulin-like growth factor-binding protein 7 isoform 2; Insulin-like growth factor-binding protein 7; insulin-like growth factor-binding protein 7; IGFBP-rP1; angiomodulin; IGF-binding protein 7; PGI2-stimulating factor; tumor-derived adhesion factor; prostacyclin-stimulating factor; insulin-like growth factor binding protein 7; IGFBP-rP1; MAC25 protein; PGI2-stimulating factor; Prostacyclin-stimulating factor; Tumor-derived adhesion factor; TAF

products gene name :

IGFBP7

other gene names :

IGFBP7; IGFBP7; AGM; PSF; TAF; FSTL2; IBP-7; MAC25; IGFBP-7; RAMSVPS; IGFBP-7v; IGFBPRP1; MAC25; PSF; IBP-7; IGF-binding protein 7; IGFBP-7; TAF

uniprot entry name :

IBP7_HUMAN

reactivity :

Human

sequence length :

279

specificity :

This assay has high sensitivity and excellent specificity for detection of human IGFBP7. No significant cross-reactivity or interference between human IGFBP7 and analogues was observed.

storage stability :

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

other info1 :

Samples: Serum, plasma and cell culture supernates. Assay Type: Sandwich. Detection Range: 0.156 ng/ml -10 ng/ml. Sensitivity: The minimum detectable dose of human IGFBP7 is typically less than 0.039 ng/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations.

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.

products description :

Principle of the assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for IGFBP7 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any IGFBP7 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for IGFBP7 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of IGFBP7 bound in the initial step. The color development is stopped and the intensity of the color is measured.

ncbi gi num :

359465608

ncbi acc num :

NP_001240764.1

ncbi gb acc num :

NM_001253835.1

uniprot acc num :

Q16270

ncbi mol weight :

29,130 Da

ncbi pathways :

Cellular Senescence Pathway (905991); Cellular Responses To Stress Pathway (645258); Senescence And Autophagy Pathway (198780); Senescence-Associated Secretory Phenotype (SASP) Pathway (905996)

ncbi summary :

This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm (PMID:21835307). [provided by RefSeq, Dec 2011]

uniprot summary :

Function: Binds IGF-I and IGF-II with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion.2 PublicationsManual assertion based on experiment in:Ref.8

size1 :

48-Strip-Wells

price1 :

565 USD

size2 :

96-Strip-Wells

price2 :

810

size3 :

5x96-Strip-Wells

price3 :

2750

size4 :

10x96-Strip-Wells

price4 :

5150

more info or order :

MyBioSource product webpage