ELISA/assay

Mouse Angiotensin converting enzyme 2, ACE2 ELISA Kit

MBS706114

96 Strip Wells

760 USD

ELISA Kit

Mouse Angiotensin converting enzyme 2, ACE2 ELISA Kit

Angiotensin converting enzyme 2 (ACE2)

Mouse Angiotensin converting enzyme 2 (ACE2) ELISA Kit; ACEH; DKFZp434A014; ACE-related carboxypeptidase; angiotensin I converting enzyme 2; angiotensin converting enzyme-like protein; Angiotensin converting enzyme 2 (ACE2)

angiotensin-converting enzyme 2; Angiotensin-converting enzyme 2; angiotensin-converting enzyme 2; ACE-related carboxypeptidase; angiotensin I converting enzyme 2; angiotensin I converting enzyme (peptidyl-dipeptidase A) 2; ACE-related carboxypeptidaseCleaved into the following chain:Processed angiotensin-converting enzyme 2

ACE2

Ace2; Ace2; 2010305L05Rik

ACE2_MOUSE

Mouse

805

This assay has high sensitivity and excellent specificity for detection of Mouse ACE2. No significant cross-reactivity or interference between Mouse ACE2 and analogues was observed.

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV% is less than 8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV% is less than 10%. Three samples of known concentration were tested in twenty assays to assess. Detection Wavelength: 450 nm

Sample Volume: 50-100ul. Protein Biological Process 1: Immunity. Protein Biological Process 3: Host-virus interaction

Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for ACE2 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any ACE2 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for ACE2 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of ACE2 bound in the initial step. The color development is stopped and the intensity of the color is measured.

194473667

NP_001123985.1

NM_001130513.1

Q8R0I0

92,368 Da

Metabolism Of Angiotensinogen To Angiotensins Pathway 1000416!!Metabolism Of Proteins Pathway 970583!!Peptide Hormone Metabolism Pathway 1000413!!Protein Digestion And Absorption Pathway 172853!!Protein Digestion And Absorption Pathway 171868!!Renin-angiotensin System Pathway 83272!!Renin-angiotensin System Pathway 486

Function: Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. May be an important regulator of heart function. May have a protective role in acute lung injury.3 PublicationsManual assertion based on experiment in:Ref.3. Catalytic activity: Angiotensin II + H2O = angiotensin-1-7 + L-phenylalanine. Cofactor: Binds 1 zinc ion per subunit

96 Strip Wells

760 USD