catalog number :
MBS705929
products type :
ELISA Kit
products full name :
Mouse tumor necrosis factor-like ligand 1, TL1 ELISA Kit
products short name :
tumor necrosis factor (ligand) superfamily, member 15
products name syn :
Mouse tumor necrosis factor-like ligand 1 (TL1) ELISA kit; MGC129934; MGC129935; TL1; TL1A; VEGI; VEGI192A; TNF ligand-related molecule 1; TNF superfamily ligand TL1A; vascular endothelial cell growth inhibitor; vascular endothelial growth inhibitor-192A; tumor necrosis factor (ligand) superfamily; member 15
other names :
tumor necrosis factor ligand superfamily member 15; Tumor necrosis factor ligand superfamily member 15; tumor necrosis factor ligand superfamily member 15; TNF ligand-related molecule 1; vascular endothelial growth inhibitor; vascular endothelial cell growth inhibitor; bM20K13.3 (tumor necrosis factor (ligand) superfamily, member 15); tumor necrosis factor (ligand) superfamily, member 15; TNF ligand-related molecule 1; Vascular endothelial cell growth inhibitor
products gene name :
TNFSF15
other gene names :
Tnfsf15; Tnfsf15; Tl1; Tl1a; Vegi; Tl1; Vegi
uniprot entry name :
TNF15_MOUSE
specificity :
This assay has high sensitivity and excellent specificity for detection of mouse TL1. No significant cross-reactivity or interference between mouse TL1 and analogues was observed.
storage stability :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
other info1 :
Samples: Serum, plasma, tissue homogenates. Assay Type: Sandwich. Detection Range: 62.5 pg/ml-4000 pg/ml. Sensitivity: Typically less than 15.6 pg/ml
other info2 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
products description :
Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for TL1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any TL1 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for TL1 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of TL1 bound in the initial step. The color development is stopped and the intensity of the color is measured.
ncbi acc num :
NP_796345.3
ncbi gb acc num :
NM_177371.3
ncbi mol weight :
27,723 Da
ncbi pathways :
Cytokine-cytokine Receptor Interaction Pathway (83248); Cytokine-cytokine Receptor Interaction Pathway (460)
uniprot summary :
Function: Receptor for TNFRSF25 and TNFRSF6B. Mediates activation of NF-kappa-B. Inhibits vascular endothelial growth and angiogenesis (in vitro). Promotes activation of caspases and apoptosis Promotes splenocyte alloactivation.1 PublicationManual assertion based on experiment in:Ref.1
size4 :
10x96-Strip-Wells