catalog number :
MBS705880
products type :
ELISA Kit
products full name :
Monkey Complement 3, C3 ELISA Kit
products short name :
Complement 3 (C3)
products name syn :
Monkey Complement 3 (C3) ELISA Kit; AHUS5; ARMD9; ASP; CPAMD1; acylation-stimulating protein cleavage product; complement component C3; Complement 3 (C3)
other names :
complement C3 preproprotein; Complement C3; complement C3; complement component 3; C3adesArg
other gene names :
C3; C3; ASP
uniprot entry name :
CO3_BOVIN
specificity :
This assay has high sensitivity and excellent specificity for detection of monkey C3. No significant cross-reactivity or interference between monkey C3 and analogues was observed.
storage stability :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
other info1 :
Samples: Serum, plasma, cell culture supernates. Assay Type: Quantitative Sandwich. Sensitivity: Typically less than 1.17 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
products description :
Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for C3 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any C3 present is bound by the immobilized antibody. After removing any unbound substances, a Horseradish Peroxidase (HRP)-conjugated antibody specific for C3 is added to the wells. Following a wash to remove any unbound reagent, a substrate solution is added to the wells and color develops in proportion to the amount of C3 bound in the initial step. The color development is stopped and the intensity of the color is measured.
ncbi acc num :
NP_001035559.2
ncbi gb acc num :
NM_001040469.2
ncbi mol weight :
187,253 Da
ncbi pathways :
Activation Of C3 And C5 Pathway (1009150); Adaptive Immune System Pathway (1009080); Alternative Complement Activation Pathway (1009149); Chagas Disease (American Trypanosomiasis) Pathway (147808); Chagas Disease (American Trypanosomiasis) Pathway (147795); Class A/1 (Rhodopsin-like Receptors) Pathway (1008554); Complement Activation, Classical Pathway (920897); Complement And Coagulation Cascades Pathway (920919); Complement And Coagulation Cascades Pathway (84312); Complement And Coagulation Cascades Pathway (484)
uniprot summary :
Function: C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates
size4 :
10x96-Strip-Wells