product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Human Superoxide dismutase [Cu-Zn], SOD1 ELISA Kit
catalog :
MBS705863
quantity :
48-Strip-Wells
price :
565 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS705863
products type :
ELISA Kit
products full name :
Human Superoxide dismutase [Cu-Zn], SOD1 ELISA Kit
products short name :
superoxide dismutase 1, soluble
products name syn :
Human Superoxide dismutase [Cu-Zn] (SOD1) ELISA kit; ALS; ALS1; IPOA; SOD; homodimer; Cu/Zn superoxide dismutase; SOD; soluble; indophenoloxidase A; superoxide dismutase; cystolic; superoxide dismutase 1; soluble
other names :
superoxide dismutase; Superoxide dismutase [Cu-Zn]; superoxide dismutase [Cu-Zn]; superoxide dismutase [Cu-Zn]; SOD, soluble; indophenoloxidase A; Cu/Zn superoxide dismutase; superoxide dismutase, cystolic; epididymis secretory protein Li 44; superoxide dismutase 1, soluble; Superoxide dismutase 1; hSod1
products gene name :
SOD1
other gene names :
SOD1; SOD1; ALS; SOD; ALS1; IPOA; hSod1; HEL-S-44; homodimer; hSod1
uniprot entry name :
SODC_HUMAN
reactivity :
Human
sequence length :
154
specificity :
This assay has high sensitivity and excellent specificity for detection of Human SOD1. No significant cross-reactivity or interference between Human SOD1 and analogues was observed.
storage stability :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
other info1 :
Samples: Serum, plasma, cell culture supernates. Assay Type: Sandwich. Detection Range: 15.6 pg/ml-1000 pg/ml. Sensitivity: 3.9 pg/ml
other info2 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV% is less than 8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV% is less than 10%. Three samples of known concentration were tested in twenty assays to assess. Detection Wavelength: 450 nm. Sample Volume: 50-100ul
products description :
Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for SOD1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any SOD1 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for SOD1 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of SOD1 bound in the initial step. The color development is stopped and the intensity of the color is measured.
ncbi gi num :
4507149
ncbi acc num :
NP_000445.1
ncbi gb acc num :
NM_000454.4
uniprot acc num :
P00441
ncbi mol weight :
15,936 Da
ncbi pathways :
AGE/RAGE Pathway (698754); Amyotrophic Lateral Sclerosis (ALS) Pathway (920975); Amyotrophic Lateral Sclerosis (ALS) Pathway (83099); Amyotrophic Lateral Sclerosis (ALS) Pathway (511); Cellular Responses To Stress Pathway (645258); Detoxification Of Reactive Oxygen Species Pathway (941400); Dopamine Metabolism Pathway (920995); FOXA1 Transcription Factor Network Pathway (137979); Folate Metabolism Pathway (198833); Hemostasis Pathway (106028)
ncbi summary :
The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. [provided by RefSeq, Jul 2008]
uniprot summary :
Function: Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Catalytic activity: 2 superoxide + 2 H+ = O2 + H2O2. Cofactor: Binds 1 copper ion per subunit.1 PublicationManual assertion based on experiment in:Ref.41
size1 :
48-Strip-Wells
price1 :
565 USD
size2 :
96-Strip-Wells
price2 :
810
size3 :
5x96-Strip-Wells
price3 :
2750
size4 :
10x96-Strip-Wells
price4 :
5150
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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