ELISA/assay

Fish lysozyme (renal amyloidosis) , LZM ELISA Kit

MBS705789

96 Strip Wells

850 USD

ELISA Kit

Fish lysozyme (renal amyloidosis) , LZM ELISA Kit

lysozyme (renal amyloidosis) (LZM)

Fish lysozyme (renal amyloidosis) (LZM) ELISA kit; lysozyme (renal amyloidosis) (LZM)

lysozyme (EC 3.2.1.17); Lysozyme C; lysozyme C; c-type lysozyme; 1,4-beta-N-acetylmuramidase C; lysozyme; 1,4-beta-N-acetylmuramidase C

LZM

LYZ; LYZ; LZM; LZM

LYSC_HUMAN

Fish

148

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

Sample Type: serum, plasma. Detection Range: 3.12 ng/ml-200 ng/ml. Detection Wavelength: 450 nm. Sensitivity: 1.56 ng/ml

Sample Volume: 50-100ul

Principle of the Assay: This assay employs the competitive inhibition enzyme immunoassay technique. An antibody specific to LZM has been pre-coated onto a microplate. Standards or samples are added to the appropriate microtiter plate wells with HRP-conjugated LZM and incubated. A competitive inhibition reaction is launched between LZM (Standards or samples) and HRP-conjugated LZM with the pre-coated antibody specific for LZM. The more amount of LZM in samples, the less antibody bound by HRP-conjugated LZM. Then the substrate solutions are added to the wells, respectively. And the color develops in opposite to the amount of LZM in the sample. The color development is stopped and the intensity of the color is measured.

307142

AAA59536.1

P61626

16,537 Da

Amyloids Pathway 366238!!C-MYB Transcription Factor Network Pathway 138073!!Disease Pathway 530764!!Salivary Secretion Pathway 153376!!Salivary Secretion Pathway 153352

This gene encodes human lysozyme, whose natural substrate is the bacterial cell wall peptidoglycan (cleaving the beta[1-4]glycosidic linkages between N-acetylmuramic acid and N-acetylglucosamine). Lysozyme is one of the anti-microbial agents found in human milk, and is also present in spleen, lung, kidney, white blood cells, plasma, saliva, and tears. Missense mutations in LYZ have been identified in heritable renal amyloidosis. [provided by RefSeq, Jul 2008]

Function: Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Catalytic activity: Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.

96 Strip Wells

850 USD