Human Beta-microseminoprotein, MSMB/PRSP ELISA Kit | MyBioSource MBS705775 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human Beta-microseminoprotein, MSMB/PRSP ELISA Kit

catalog :

MBS705775

quantity :

48-Strip-Wells

price :

565 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS705775

products type :

ELISA Kit

products full name :

Human Beta-microseminoprotein, MSMB/PRSP ELISA Kit

products short name :

microseminoprotein, beta-

products name syn :

Human Beta-microseminoprotein (MSMB/PRSP) ELISA kit; RP11-481A12.1; HPC13; IGBF; MSP; MSPB; PN44; PRPS; PSP; PSP-94; PSP57; PSP94; beta-microseminoprotein; immunoglobulin binding factor; prostate secreted seminal plasma protein; prostatic secretory prote; microseminoprotein; beta-

other names :

beta-microseminoprotein isoform a; Beta-microseminoprotein; beta-microseminoprotein; seminal plasma beta-inhibin; immunoglobulin binding factor; prostate secreted seminal plasma protein; prostate secretory protein of 94 amino acids; microseminoprotein, beta-; Immunoglobulin-binding factor; IGBF; PN44; Prostate secreted seminal plasma protein; Prostate secretory protein of 94 amino acids; PSP-94; PSP94; Seminal plasma beta-inhibin

products gene name :

MSMB

other gene names :

MSMB; MSMB; MSP; PSP; IGBF; MSPB; PN44; PRPS; HPC13; PSP57; PSP94; PSP-94; PRSP; IGBF; PSP-94; PSP94

uniprot entry name :

MSMB_HUMAN

reactivity :

Human

sequence length :

114

specificity :

This assay has high sensitivity and excellent specificity for detection of Human MSMB. No significant cross-reactivity or interference between Human MSMB and analogues was observed.

storage stability :

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

other info1 :

Samples: Serum, plasma, tissue homogenates. Assay Type: Sandwich. Detection Range: 2.5 ng/ml-80 ng/ml. Sensitivity: 1.25 ng/ml

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV% is less than 8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV% is less than 10%. Three samples of known concentration were tested in twenty assays to assess. Detection Wavelength: 450 nm. Sample Volume: 50-100ul

products description :

Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for MSMB has been pre-coated onto a microplate. Standards and samples are pipetted into the wells with a Horseradish Peroxidase (HRP) conjugated antibody specific for MSMB. Following a wash to remove any unbound reagent, a substrate solution is added to the wells and color develops in proportion to the amount of MSMB bound in the initial step. The color development is stopped and the intensity of the color is measured.

ncbi gi num :

4557036

ncbi acc num :

NP_002434.1

ncbi gb acc num :

NM_002443.3

uniprot acc num :

P08118

ncbi mol weight :

12,865 Da

ncbi pathways :

Focal Adhesion Pathway (83067); Focal Adhesion Pathway (478); MAPK Signaling Pathway (83048); MAPK Signaling Pathway (456); Salmonella Infection Pathway (375172); Salmonella Infection Pathway (375149)

ncbi summary :

The protein encoded by this gene is a member of the immunoglobulin binding factor family. It is synthesized by the epithelial cells of the prostate gland and secreted into the seminal plasma. This protein has inhibin-like activity. It may have a role as an autocrine paracrine factor in uterine, breast and other female reproductive tissues. The expression of the encoded protein is found to be decreased in prostate cancer. Two alternatively spliced transcript variants encoding different isoforms are described for this gene. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008]

uniprot summary :

MSMB: Defects in MSMB are the cause of susceptibility to prostate cancer hereditary type 13 (HPC13). It is a condition associated with familial predisposition to cancer of the prostate. Most prostate cancers are adenocarcinomas that develop in the acini of the prostatic ducts. Other rare histopathologic types of prostate cancer that occur in approximately 5% of patients include small cell carcinoma, mucinous carcinoma, prostatic ductal carcinoma, transitional cell carcinoma, squamous cell carcinoma, basal cell carcinoma, adenoid cystic carcinoma (basaloid), signet-ring cell carcinoma and neuroendocrine carcinoma. Belongs to the beta-microseminoprotein family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 10q11.2. Cellular Component: extracellular space; nucleus. Disease: Prostate Cancer, Hereditary, 13

size1 :

48-Strip-Wells

price1 :

565 USD

size2 :

96-Strip-Wells

price2 :

810

size3 :

5x96-Strip-Wells

price3 :

2750

size4 :

10x96-Strip-Wells

price4 :

5150

more info or order :

MyBioSource product webpage