Human Ferritin, Heavy Polypeptide, FTH ELISA Kit | MyBioSource MBS705764 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human Ferritin, Heavy Polypeptide, FTH ELISA Kit

catalog :

MBS705764

quantity :

48-Strip-Wells

price :

565 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS705764

products type :

ELISA Kit

products full name :

Human Ferritin, Heavy Polypeptide, FTH ELISA Kit

products short name :

ferritin, heavy polypeptide 1

products name syn :

Human Ferritin; Heavy Polypeptide (FTH) ELISA Kit; FHC; FTH; FTHL6; MGC104426; PIG15; PLIF; apoferritin; placenta immunoregulatory factor; proliferation-inducing protein 15; ferritin; heavy polypeptide 1

other names :

ferritin heavy chain; Ferritin heavy chain; ferritin heavy chain; apoferritin; ferritin H subunit; placenta immunoregulatory factor; proliferation-inducing protein 15; cell proliferation-inducing gene 15 protein; ferritin, heavy polypeptide 1; Cell proliferation-inducing gene 15 proteinCleaved into the following chain:Ferritin heavy chain, N-terminally processed

products gene name :

FTH1

other gene names :

FTH1; FTH1; FHC; FTH; HFE5; PLIF; FTHL6; PIG15; FTH; FTHL6; OK/SW-cl.84; PIG15; Ferritin H subunit

uniprot entry name :

FRIH_HUMAN

reactivity :

Human

sequence length :

183

specificity :

This assay has high sensitivity and excellent specificity for detection of human FTH. No significant cross-reactivity or interference between human FTH and analogues was observed.

storage stability :

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

other info1 :

Samples: Serum, plasma, cell culture supernates, tissue homogenates. Assay Type: Sandwich. Detection Range: 0.45 ng/ml -30 ng/ml. Sensitivity: 0.11 ng /ml.

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.

products description :

Principle of the Assay This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for FTH has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any FTH present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for FTH is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of FTH bound in the initial step. The color development is stopped and the intensity of the color is measured.

ncbi gi num :

56682959

ncbi acc num :

NP_002023.2

ncbi gb acc num :

NM_002032.2

uniprot acc num :

P02794

ncbi mol weight :

21,226 Da

ncbi pathways :

Binding And Uptake Of Ligands By Scavenger Receptors Pathway (771599); Clathrin Derived Vesicle Budding Pathway (119545); Golgi Associated Vesicle Biogenesis Pathway (119546); Iron Metabolism In Placenta Pathway (672461); Iron Uptake And Transport Pathway (187191); Membrane Trafficking Pathway (106160); Mineral Absorption Pathway (212237); Mineral Absorption Pathway (212220); Scavenging By Class A Receptors Pathway (833814); Transmembrane Transport Of Small Molecules Pathway (106572)

ncbi summary :

This gene encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]

uniprot summary :

Function: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney . Catalytic activity: 4 Fe2+ + 4 H+ + O2 = 4 Fe3+ + 2 H2O.

size1 :

48-Strip-Wells

price1 :

565 USD

size2 :

96-Strip-Wells

price2 :

810

size3 :

5x96-Strip-Wells

price3 :

2750

size4 :

10x96-Strip-Wells

price4 :

5150

more info or order :

MyBioSource product webpage