catalog number :
MBS705710
products type :
ELISA Kit
products full name :
Human CC-Chemokine Receptor 5, CCR5 ELISA Kit
products short name :
chemokine (C-C motif) receptor 5
products name syn :
Human CC-Chemokine Receptor 5 (CCR5) ELISA Kit; CC-CKR-5; CCCKR5; CD195; CKR-5; CKR5; CMKBR5; FLJ78003; IDDM22; C-C chemokine receptor type 5; C-C motif chemokine receptor 5 A159A; OTTHUMP00000209784; chemokine receptor CCR5; chemr13; chemokine (C-C motif) receptor 5
other names :
C-C chemokine receptor type 5; C-C chemokine receptor type 5; C-C chemokine receptor type 5; CCR-5; CC-CKR-5; C-C CKR-5; chemokine C-C motif receptor 5; chemokine (C-C motif) receptor 5<; CD_antigen: CD195
products gene name :
CCR5
other gene names :
CCR5; CCR5; CMKBR5; C-C CKR-5; CC-CKR-5; CCR-5; CCR5
uniprot entry name :
CCR5_BOVIN
specificity :
This assay has high sensitivity and excellent specificity for detection of Human CCR5. No significant cross-reactivity or interference between Human CCR5 and analogues was observed.
storage stability :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
other info1 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV% is less than 8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV% is less than 10%. Three samples of known concentration were tested in twenty assays to assess. Sample Type: serum, plasma and cell culture supernates. Detection Range: 15.6 pg/ml-1000 pg/ml. Detection Wavelength: 450 nm. Sensitivity: 3.9 pg/ml
other info2 :
Sample Volume: 50-100ul
products description :
Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with a goat-anti-rabbit antibody. Standards or samples are then added to the appropriate microtiter plate wells with a HRP-conjugated PGH2 and antibody preparation specific for PGH2 and incubated. Then substrate solutions are added to each well. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The concentration of PGH2 in the samples is then determined by comparing the O.D. of the samples to the standard curve.
ncbi acc num :
NP_001011672.2
ncbi gb acc num :
NM_001011672.2
ncbi mol weight :
40,235 Da
ncbi pathways :
Chemokine Receptors Bind Chemokines Pathway 1008556!!Chemokine Signaling Pathway 98761!!Chemokine Signaling Pathway 96864!!Class A/1 (Rhodopsin-like Receptors) Pathway 1008554!!Cytokine-cytokine Receptor Interaction Pathway 84290!!Cytokine-cytokine Receptor Interaction Pathway 460!!Endocytosis Pathway 102272!!Endocytosis Pathway 102181!!G Alpha (i) Signalling Events Pathway 1008584!!GPCR Downstream Signaling Pathway 1008582
uniprot summary :
Function: Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation