ELISA/assay

Bovine Fibroblast Growth Factor 23, FGF23 ELISA Kit

MBS705677

96 Strip Wells

850 USD

ELISA Kit

Bovine Fibroblast Growth Factor 23, FGF23 ELISA Kit

Fibroblast Growth Factor 23 (FGF23)

Bovine Fibroblast Growth Factor 23 (FGF23) ELISA Kit; Fibroblast Growth Factor 23 (FGF23)

fibroblast growth factor 23; Fibroblast growth factor 23; fibroblast growth factor 23; phosphatonin; tumor-derived hypophosphatemia inducing factor; fibroblast growth factor 23; Phosphatonin; Tumor-derived hypophosphatemia-inducing factorCleaved into the following 2 chains:Fibroblast growth factor 23 N-terminal peptide; Fibroblast growth factor 23 C-terminal peptide

FGF23

FGF23; FGF23; ADHR; FGFN; HYPF; HPDR2; PHPTC; HYPF; UNQ3027/PRO9828; FGF-23

FGF23_HUMAN

Bovine

251

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

Detection Wavelength: 450 nm

Sample Volume: 50-100ul

Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with an antibody specific to CTX-II. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific for CTX-II and Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then a TMB (3,3',5,5' tetramethyl-benzidine) substrate solution is added to each well. Only those wells that contain CTX-II, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The concentration of CTX-II in the samples is then determined by comparing the O.D. of the samples to the standard curve.

10190674

NP_065689.1

NM_020638.2

Q9GZV9

27,954 Da

Activated Point Mutants Of FGFR2 Pathway 645281!!Adaptive Immune System Pathway 366160!!Constitutive PI3K/AKT Signaling In Cancer Pathway 685535!!DAP12 Interactions Pathway 685549!!DAP12 Signaling Pathway 685550!!Disease Pathway 530764!!Downstream Signal Transduction Pathway 106385!!Downstream Signaling Events Of B Cell Receptor (BCR) Pathway 576250!!Downstream Signaling Of Activated FGFR Pathway 160957!!FGF Signaling Pathway 137989

This gene encodes a member of the fibroblast growth factor family of proteins, which possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. The product of this gene regulates phosphate homeostasis and transport in the kidney. The full-length, functional protein may be deactivated via cleavage into N-terminal and C-terminal chains. Mutation of this cleavage site causes autosomal dominant hypophosphatemic rickets (ADHR). Mutations in this gene are also associated with hyperphosphatemic familial tumoral calcinosis (HFTC). [provided by RefSeq, Feb 2013]

Function: Regulator of phosphate homeostasis. Inhibits renal tubular phosphate transport by reducing SLC34A1 levels. Upregulates EGR1 expression in the presence of KL Acts directly on the parathyroid to decrease PTH secretion Regulator of vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralization.5 PublicationsManual assertion based on experiment in:Ref.2

96 Strip Wells

850 USD