product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Human anti-beta1-adrenergic receptor, beta1AR autoantibody ELISA Kit
catalog :
MBS705603
quantity :
48-Strip-Wells
price :
510 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS705603
products type :
ELISA Kit
products full name :
Human anti-beta1-adrenergic receptor, beta1AR autoantibody ELISA Kit
products short name :
anti-beta1-adrenergic receptor (beta1AR) autoantibody
products name syn :
Human anti-beta1-adrenergic receptor (beta1AR) autoantibody ELISA Kit; anti-beta1-adrenergic receptor (beta1AR) autoantibody
other names :
beta-1 adrenergic receptor; Beta-1 adrenergic receptor; beta-1 adrenergic receptor; beta-1 adrenoceptor; beta-1 adrenoreceptor; adrenergic, beta-1-, receptor; adrenoceptor beta 1; Beta-1 adrenoreceptor; Beta-1 adrenoceptor
other gene names :
ADRB1; ADRB1; RHR; B1AR; ADRB1R; BETA1AR; ADRB1R; B1AR; Beta-1 adrenoceptor
uniprot entry name :
ADRB1_HUMAN
reactivity :
Human
sequence length :
477
specificity :
This assay has high sensitivity and excellent specificity for detection of human anti-beta1AR autoantibody. No significant cross-reactivity or interference between human anti-beta1AR autoantibody and analogues was observed.
storage stability :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
other info1 :
Samples: Serum
other info2 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<10%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
products description :
Principle of the assay: This assay employs the qualitative enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with antigen. Samples are pipetted into the wells with anti-human immunoglobulin conjugated Horseradish Peroxidase (HRP). Any antibodies specific for the antigen present will bind to the pre-coated antigen. Following a wash to remove any unbound reagent, a substrate solution is added to the wells and color develops in proportion to the amount of human anti-beta1AR autoantibody bound in the initial step. The color development is stopped and the intensity of the color is measured.
ncbi gi num :
4557265
ncbi acc num :
NP_000675.1
ncbi gb acc num :
NM_000684.2
uniprot acc num :
P08588
ncbi mol weight :
51,323 Da
ncbi pathways :
Adrenergic Signaling In Cardiomyocytes Pathway (908257); Adrenergic Signaling In Cardiomyocytes Pathway (909696); Adrenoceptors Pathway (106365); Amine Ligand-binding Receptors Pathway (106363); Calcium Regulation In The Cardiac Cell Pathway (198906); Calcium Signaling Pathway (83050); Calcium Signaling Pathway (459); Class A/1 (Rhodopsin-like Receptors) Pathway (106357); Dilated Cardiomyopathy Pathway (121494); Dilated Cardiomyopathy Pathway (121285)
ncbi summary :
The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure. [provided by RefSeq, Jul 2008]
uniprot summary :
Function: Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. Mediates Ras activation through G(s)-alpha- and cAMP-mediated signaling.1 PublicationManual assertion based on experiment in:Ref.6
size1 :
48-Strip-Wells
price1 :
510 USD
size2 :
96-Strip-Wells
price2 :
725
size3 :
5x96-Strip-Wells
price3 :
2565
size4 :
10x96-Strip-Wells
price4 :
4800
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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