Human tumor necrosis factor superfamily 15, TL1A/TNFSF15 ELISA Kit | MyBioSource MBS705475 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human tumor necrosis factor superfamily 15, TL1A/TNFSF15 ELISA Kit

catalog :

MBS705475

quantity :

48-Strip-Wells

price :

510 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS705475

products type :

ELISA Kit

products full name :

Human tumor necrosis factor superfamily 15, TL1A/TNFSF15 ELISA Kit

products short name :

tumor necrosis factor (ligand) superfamily, member 15

products name syn :

Human tumor necrosis factor superfamily 15 (TL1A/TNFSF15) ELISA Kit; MGC129934; MGC129935; TL1; TL1A; VEGI; VEGI192A; TNF ligand-related molecule 1; TNF superfamily ligand TL1A; vascular endothelial cell growth inhibitor; vascular endothelial growth inhibitor-192A; tumor necrosis factor (ligand) superfamily; member 15

other names :

tumor necrosis factor ligand superfamily member 15 isoform VEGI-192; Tumor necrosis factor ligand superfamily member 15; tumor necrosis factor ligand superfamily member 15; TNF superfamily ligand TL1A; TNF ligand-related molecule 1; vascular endothelial cell growth inhibitor; vascular endothelial growth inhibitor-192A; tumor necrosis factor (ligand) superfamily, member 15; TNF ligand-related molecule 1; Vascular endothelial cell growth inhibitorCleaved into the following 2 chains:Tumor necrosis factor ligand superfamily member 15, membrane form; Tumor necrosis factor ligand superfamily member 15, secreted form

products gene name :

TNFSF15

other gene names :

TNFSF15; TNFSF15; TL1; TL1A; VEGI; VEGI192A; TL1; VEGI

uniprot entry name :

TNF15_HUMAN

reactivity :

Human

sequence length :

192

specificity :

This assay has high sensitivity and excellent specificity for detection of Human TNFSF15. No significant cross-reactivity or interference between Human TNFSF15 and analogues was observed.

storage stability :

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV% is less than 8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV% is less than 10%. Three samples of known concentration were tested in twenty assays to assess. Detection Wavelength: 450 nm. Sample Volume: 50-100ul

products description :

Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with an antibody specific to TL1A. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific for TL1A and Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then a TMB (3,3',5,5' tetramethyl-benzidine) substrate solution is added to each well. Only those wells that contain TL1A, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The concentration of TL1A in the samples is then determined by comparing the O.D. of the samples to the standard curve.

ncbi gi num :

324072728

ncbi acc num :

NP_001191273.1

ncbi gb acc num :

NM_001204344.1

uniprot acc num :

O95150

ncbi mol weight :

28,087 Da

ncbi pathways :

Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); Senescence And Autophagy Pathway (198780)

ncbi summary :

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011]

uniprot summary :

Function: Receptor for TNFRSF25 and TNFRSF6B. Mediates activation of NF-kappa-B. Inhibits vascular endothelial growth and angiogenesis (in vitro). Promotes activation of caspases and apoptosis.4 PublicationsManual assertion based on experiment in:Ref.1

size1 :

48-Strip-Wells

price1 :

510 USD

size2 :

96-Strip-Wells

price2 :

725

size3 :

5x96-Strip-Wells

price3 :

2565

size4 :

10x96-Strip-Wells

price4 :

4800

more info or order :

MyBioSource product webpage