ELISA/assay

Human Syndecan-1/CD138, SDC1 ELISA Kit

MBS705458

48-Strip-Wells

370 USD

ELISA Kit

Human Syndecan-1/CD138, SDC1 ELISA Kit

syndecan 1

Human Syndecan-1/CD138 (SDC1) ELISA Kit; CD138; SDC; SYND1; syndecan; CD138 antigen; heparan sulfate proteoglycan fibroblast growth factor receptor; syndecan proteoglycan 1; syndecan 1

syndecan-1; Syndecan-1; syndecan-1; CD138 antigen; syndecan proteoglycan 1; heparan sulfate proteoglycan fibroblast growth factor receptor; syndecan 1; CD_antigen: CD138

SDC1

SDC1; SDC1; SDC; CD138; SYND1; syndecan; SDC; SYND1

SDC1_HUMAN

Human

310

This assay has high sensitivity and excellent specificity for detection of Human SDC1. No significant cross-reactivity or interference between Human SDC1 and analogues was observed.

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

Samples: Serum, plasma, tissue homogenates. Assay Type: Sandwich. Detection Range: 4.7 ng/ml-300 ng/ml. Sensitivity: 1.18 ng/ml

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV% is less than 8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV% is less than 10%. Three samples of known concentration were tested in twenty assays to assess. Detection Wavelength: 450 nm. Sample Volume: 50-100ul

Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for SDC1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any SDC1 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for SDC1 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of SDC1 bound in the initial step. The color development is stopped and the intensity of the color is measured.

55749480

NP_001006947.1

NM_001006946.1

P18827

32,462 Da

A Tetrasaccharide Linker Sequence Is Required For GAG Synthesis Pathway (645305); Arf6 Trafficking Events Pathway (137954); Cell Adhesion Molecules (CAMs) Pathway (83069); Cell Adhesion Molecules (CAMs) Pathway (480); Chondroitin Sulfate/dermatan Sulfate Metabolism Pathway (645308); Chylomicron-mediated Lipid Transport Pathway (106157); Disease Pathway (530764); Diseases Associated With Visual Transduction Pathway (771581); ECM-receptor Interaction Pathway (83068); ECM-receptor Interaction Pathway (479)

The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein. [provided by RefSeq, Jul 2008]

Function: Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix.

48-Strip-Wells

370 USD

96-Strip-Wells

525

5x96-Strip-Wells

2025

10x96-Strip-Wells

3775