catalog number :
MBS705419
products type :
ELISA Kit
products full name :
Pig glial fibrillary acidic protein, GFAP ELISA Kit
products short name :
glial fibrillary acidic protein, GFAP
products name syn :
Pig glial fibrillary acidic protein; GFAP ELISA Kit; glial fibrillary acidic protein; GFAP
other names :
glial fibrillary acidic protein; Glial fibrillary acidic protein; glial fibrillary acidic protein; glial fibrillary acidic protein
products gene name :
GFAP
other gene names :
GFAP; GFAP; GFAP
uniprot entry name :
GFAP_HUMAN
specificity :
This assay has high sensitivity and excellent specificity for detection of pig GFAP. No significant cross-reactivity or interference between pig GFAP and analogues was observed.
storage stability :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
other info1 :
Samples: Serum, plasma and tissue homogenates. Assay Type: Competitive. Detection Range: 0.1 ng/ml-20 ng/ml. Sensitivity: Typically less than 0.05 ng/ml
other info2 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<15%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<15%. Three samples of known concentration were tested in twenty assays to assess.
products description :
Principle of the Assay: This assay employs the competitive inhibition enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with goat-anti-rabbit antibody. Standards or samples are added to the appropriate microtiter plate wells with an antibody specific for GFAP and Horseradish Peroxidase (HRP) conjugated GFAP. The competitive inhibition reaction is launched between with HRP labeled GFAP and unlabeled GFAP with the antibody. A substrate solution is added to the wells and the color develops in opposite to the amount of GFAP in the sample. The color development is stopped and the intensity of the color is measured.
ncbi acc num :
AAB22581.1
ncbi mol weight :
49,508 Da
ncbi pathways :
Neural Crest Differentiation Pathway (672460); Nuclear Signaling By ERBB4 Pathway (530744); Signal Transduction Pathway (477114); Signaling By ERBB4 Pathway (530741); Spinal Cord Injury Pathway (739007)
ncbi summary :
This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]
uniprot summary :
Function: GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.
size4 :
10x96-Strip-Wells