catalog number :
MBS705416
products type :
ELISA Kit
products full name :
Human Syndecan-3, SDC3 ELISA Kit
products short name :
syndecan 3
products name syn :
Human Syndecan-3 (SDC3) ELISA Kit; SDCN; SYND3; N-syndecan; syndecan neural type; syndecan proteoglycan 3; syndecan 3
other names :
syndecan-3; Syndecan-3; syndecan-3; N-syndecan; syndecan neural type; syndecan proteoglycan 3; syndecan 3
products gene name :
SDC3
other gene names :
SDC3; SDC3; SDCN; SYND3; KIAA0468; SYND3
uniprot entry name :
SDC3_HUMAN
specificity :
This assay has high sensitivity and excellent specificity for detection of human SDC3. No significant cross-reactivity or interference between human SDC3 and analogues was observed.
storage stability :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
other info1 :
Samples: Serum, plasma, tissue homogenates. Assay Type: Sandwich. Detection Range: 46.88 pg/ml -3000 pg/ml. Sensitivity: 11.72 pg/ml.
other info2 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
products description :
Principle of the Assay This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for SDC3 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any SDC3 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for SDC3 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of SDC3 bound in the initial step. The color development is stopped and the intensity of the color is measured.
ncbi acc num :
NP_055469.3
ncbi gb acc num :
NM_014654.3
ncbi mol weight :
45,497 Da
ncbi pathways :
A Tetrasaccharide Linker Sequence Is Required For GAG Synthesis Pathway (645305); Cell Adhesion Molecules (CAMs) Pathway (83069); Cell Adhesion Molecules (CAMs) Pathway (480); Chondroitin Sulfate/dermatan Sulfate Metabolism Pathway (645308); Disease Pathway (530764); Diseases Associated With Visual Transduction Pathway (771581); Extracellular Matrix Organization Pathway (576262); Glycogen Storage Diseases Pathway (980468); Glycosaminoglycan Metabolism Pathway (645297); HS-GAG Biosynthesis Pathway (645306)
ncbi summary :
The protein encoded by this gene belongs to the syndecan proteoglycan family. It may play a role in the organization of cell shape by affecting the actin cytoskeleton, possibly by transferring signals from the cell surface in a sugar-dependent mechanism. Allelic variants of this gene have been associated with obesity. [provided by RefSeq, Oct 2009]
uniprot summary :
Function: Cell surface proteoglycan that may bear heparan sulfate May have a role in the organization of cell shape by affecting the actin cytoskeleton, possibly by transferring signals from the cell surface in a sugar-dependent mechanism.1 PublicationManual assertion based on experiment in:Ref.1
size4 :
10x96-Strip-Wells