catalog number :
MBS705275
products type :
ELISA Kit
products full name :
Human beta2-glycoprotein I (beta2-GPI) antibody, IgM ELISA Kit
products short name :
beta2-glycoprotein I (beta2-GPI) antibody (IgM)
products name syn :
Human beta2-glycoprotein I (beta2-GPI) antibody (IgM) ELISA kit; beta2-glycoprotein I (beta2-GPI) antibody (IgM)
other names :
beta-2-glycoprotein 1; Beta-2-glycoprotein 1; beta-2-glycoprotein 1; B2GPI; apo-H; beta(2)GPI; APC inhibitor; anticardiolipin cofactor; activated protein C-binding protein; apolipoprotein H (beta-2-glycoprotein I); APC inhibitor; Activated protein C-binding protein; Anticardiolipin cofactor; Apolipoprotein H; Apo-H; Beta-2-glycoprotein I; B2GPI; Beta(2)GPI
products gene name :
beta2-GPI
other gene names :
APOH; APOH; BG; B2G1; B2GP1; B2G1; Apo-H; B2GPI; Beta(2)GPI
uniprot entry name :
APOH_HUMAN
specificity :
This assay has high sensitivity and excellent specificity for detection of human beta2-glycoprotein I(beta2-GPI) antibody (IgM). No significant cross-reactivity or interference between human beta2-glycoprotein I(beta2-GPI) antibody (IgM) and analogues was observed.
storage stability :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
other info1 :
Samples: Serum
other info2 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<15%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<15%. Three samples of known concentration were tested in twenty assays to assess.
products description :
Principle of the assay: This assay employs the qualitative enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with antigen. Samples are pipetted into the wells with anti-human IgM conjugated Horseradish Peroxidase (HRP). Any antibodies specific for the antigen present will bind to the pre-coated antigen. Following a wash to remove any unbound reagent, a substrate solution is added to the wells and color develops in proportion to the amount of human beta2-glycoprotein I(beta2-GPI) antibody (IgM) bound in the initial step. The color development is stopped and the intensity of the color is measured.
ncbi acc num :
NP_000033.2
ncbi gb acc num :
NM_000042.2
ncbi mol weight :
38,298 Da
ncbi summary :
Apolipoprotein H has been implicated in a variety of physiologic pathways including lipoprotein metabolism, coagulation, and the production of antiphospholipid autoantibodies. APOH may be a required cofactor for anionic phospholipid binding by the antiphospholipid autoantibodies found in sera of many patients with lupus and primary antiphospholipid syndrome, but it does not seem to be required for the reactivity of antiphospholipid autoantibodies associated with infections. [provided by RefSeq, Jul 2008]
uniprot summary :
Function: Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells.
size4 :
10x96-Strip-Wells