product summary
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company name :
MyBioSource
product type :
antibody
product name :
N Antibody
catalog :
MBS7052613
quantity :
0.05 mg
price :
160 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
Lassa virus
application :
ELISA, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS7052613
products type :
Antibody
products full name :
N Antibody
products short name :
[N]
products name syn :
[Nucleoprotein; Nucleocapsid protein; Protein N; N]
other names :
[nucleoprotein; Nucleoprotein; nucleoprotein; Nucleocapsid protein; Protein N]
products gene name :
[N]
other gene names :
[LASVsSgp1; N]
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Lassa virus
purity :
>95%, Protein G purified
form :
Liquid
storage stability :
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.
tested application :
ELISA (EIA)
other info1 :
Immunogen: Recombinant Lassa virus Nucleoprotein (1-569AA). Conjugation: Non-conjugated. Storage Buffer: Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, pH 7.4. Research Area: Others
products description :
Encapsidates the genome, protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC). Serves as template for viral transcription and replication. The increased presence of protein N in host cell does not seem to trigger the switch from transcription to replication as observed in other negative strain RNA viruses. Disables the host innate defense by interfering with beta interferon (IFNB) production through the inhibition of host IRF3 phosphorylation and activation by host IKBKE. Through the interaction with host IKBKE, strongly inhibits the phosphorylation and nuclear translocation of IRF3, a protein involved in IFN activation pathway, leading to the inhibition of IFNB and IRF3-dependent promoters activation (By similarity).
ncbi gi num :
23343510
ncbi acc num :
NP_694869.1
ncbi gb acc num :
NC_004296.1
uniprot acc num :
P13699
uniprot summary :
Encapsidates the genome, protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC). Serves as template for viral transcription and replication. The increased presence of protein N in host cell does not seem to trigger the switch from transcription to replication as observed in other negative strain RNA viruses. Disables the host innate defense by interfering with beta interferon (IFNB) production through the inhibition of host IRF3 phosphorylation and activation by host IKBKE. Through the interaction with host IKBKE, strongly inhibits the phosphorylation and nuclear translocation of IRF3, a protein involved in IFN activation pathway, leading to the inhibition of IFNB and IRF3-dependent promoters activation ().
size1 :
0.05 mg
price1 :
160 USD
size2 :
0.1 mg
price2 :
235
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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