Mouse platelet-derived growth factor CC, PDGF-CC ELISA Kit | MyBioSource MBS705088 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Mouse platelet-derived growth factor CC, PDGF-CC ELISA Kit

catalog :

MBS705088

quantity :

48-Strip-Wells

price :

565 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS705088

products type :

ELISA Kit

products full name :

Mouse platelet-derived growth factor CC, PDGF-CC ELISA Kit

products short name :

platelet derived growth factor C

products name syn :

Mouse platelet-derived growth factor CC (PDGF-CC) ELISA Kit; FALLOTEIN; SCDGF; platelet-derived growth factor C; secretory growth factor-like protein; spinal cord-derived growth factor; platelet derived growth factor C

other names :

platelet-derived growth factor C; Platelet-derived growth factor C; platelet-derived growth factor C; SCDGF; VEGF-E; fallotein; spinal cord-derived growth factor; platelet-derived growth factor, C polypeptide; Fallotein; Spinal cord-derived growth factor; SCDGF; VEGF-ECleaved into the following 2 chains:Platelet-derived growth factor C, latent form; PDGFC latent form; Platelet-derived growth factor C, receptor-binding form; PDGFC receptor-binding form

products gene name :

PDGFC

other gene names :

Pdgfc; Pdgfc; PDGF-C; AI647969; 1110064L01Rik; Scdgf; PDGF-C; SCDGF; PDGFC latent form; PDGFC receptor-binding form

uniprot entry name :

PDGFC_MOUSE

reactivity :

Mouse

sequence length :

345

specificity :

This assay has high sensitivity and excellent specificity for detection of mouse PDGF-CC. No significant cross-reactivity or interference between mouse PDGF-CC and analogues was observed.

storage stability :

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

other info1 :

Samples: Serum, plasma, cell culture supernates, tissue homogenates,. Assay Type: Sandwich. Detection Range: 62.5 pg/ml-4000 pg/ml. Sensitivity: Typically less than 15.6 pg/ml

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.

products description :

Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for PDGF-CC has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any PDGF-CC present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for PDGF-CC is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of PDGF-CC bound in the initial step. The color development is stopped and the intensity of the color is measured.

ncbi gi num :

10242385

ncbi acc num :

NP_064355.1

ncbi gb acc num :

NM_019971.2

uniprot acc num :

Q8CI19

ncbi mol weight :

38,741 Da

ncbi pathways :

Cytokine-cytokine Receptor Interaction Pathway (83248); Cytokine-cytokine Receptor Interaction Pathway (460); Focal Adhesion Pathway (198353); Focal Adhesion Pathway (83264); Focal Adhesion Pathway (478); Gap Junction Pathway (83269); Gap Junction Pathway (483); Melanoma Pathway (83307); Melanoma Pathway (526); PI3K-Akt Signaling Pathway (692242)

uniprot summary :

Function: Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen and chemoattractant for cells of mesenchymal origin. Required for normal skeleton formation during embryonic development, especially for normal development of the craniofacial skeleton and for normal development of the palate. Required for normal skin morphogenesis during embryonic development. Plays an important role in wound healing, where it appears to be involved in three stages: inflammation, proliferation and remodeling. Plays an important role in angiogenesis and blood vessel development. Involved in fibrotic processes, in which transformation of interstitial fibroblasts into myofibroblasts plus collagen deposition occurs. The CUB domain has mitogenic activity in coronary artery smooth muscle cells, suggesting a role beyond the maintenance of the latency of the PDGF domain. In the nucleus, PDGFC seems to have additional function.8 PublicationsManual assertion based on experiment in:Ref.6

size1 :

48-Strip-Wells

price1 :

565 USD

size2 :

96-Strip-Wells

price2 :

810

size3 :

5x96-Strip-Wells

price3 :

2750

size4 :

10x96-Strip-Wells

price4 :

5150

more info or order :

MyBioSource product webpage