catalog number :
MBS7050579
products full name :
SLC13A5 Antibody
products short name :
[SLC13A5]
products name syn :
[Solute carrier family 13 member 5; Na(+)/citrate cotransporter; NaCT; Sodium-coupled citrate transporter; Sodium-dependent citrate transporter; SLC13A5; NACT]
other names :
[solute carrier family 13 member 5 isoform b; Solute carrier family 13 member 5; solute carrier family 13 member 5; solute carrier family 13 member 5; Na(+)/citrate cotransporter; NaCT; Sodium-coupled citrate transporter; Sodium-dependent citrate transporter]
products gene name :
[SLC13A5]
other gene names :
[SLC13A5; SLC13A5; NACT; mIndy; EIEE25; NACT; NaCT]
uniprot entry name :
S13A5_HUMAN
reactivity :
Human, Mouse, Rat
purity :
>95%, Protein G purified
storage stability :
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
app notes :
Recommended Dilution: WB: 1: 500-1: 5000. IHC: 1: 20-1: 200. IF: 1: 50-1: 200
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
image3 heading :
Immunohistochemistry (IHC)
other info1 :
Immunogen: Recombinant Human Solute carrier family 13 member 5 protein (156-204AA). Storage Buffer: Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, pH 7.4. Conjugate: Non-conjugated. Species: Human. Research Area: Signal Transduction
other info2 :
Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-169320
products description :
High-affinity sodium/citrate cotransporter that mediates citrate entry into cells. The transport process is electrogenic; it is the trivalent form of citrate rather than the divalent form that is recognized as a substrate. May facilitate the utilization of circulating citrate for the generation of metabolic energy and for the synthesis of fatty acids and cholesterol.
ncbi acc num :
NP_001137310.1
ncbi gb acc num :
NM_001143838.2
ncbi pathways :
SLC-mediated Transmembrane Transport Pathway (1269907); Sodium-coupled Sulphate, Di- And Tri-carboxylate Transporters Pathway (1269928); Transmembrane Transport Of Small Molecules Pathway (1269903); Transport Of Glucose And Other Sugars, Bile Salts And Organic Acids, Metal Ions And Amine Compounds Pathway (1269923)
ncbi summary :
This gene encodes a protein belonging to the solute carrier family 13 group of proteins. This family member is a sodium-dependent citrate cotransporter that may regulate metabolic processes. Mutations in this gene cause early infantile epileptic encephalopathy 25. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014]
uniprot summary :
SLC13A5: High-affinity sodium/citrate cotransporter that mediates citrate entry into cells. The transport process is electrogenic; it is the trivalent form of citrate rather than the divalent form that is recognized as a substrate. May facilitate the utilization of circulating citrate for the generation of metabolic energy and for the synthesis of fatty acids and cholesterol. Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family. Chromosomal Location of Human Ortholog: 17p13.1. Cellular Component: integral to plasma membrane; plasma membrane. Molecular Function: citrate transmembrane transporter activity; sodium:dicarboxylate symporter activity; succinate transmembrane transporter activity. Biological Process: citrate transport. Disease: Epileptic Encephalopathy, Early Infantile, 25