ELISA/assay

Pig Vascular cell adhesion molecule 1, VCAM-1 ELISA Kit

MBS705014

96 Strip Wells

915 USD

ELISA Kit

Pig Vascular cell adhesion molecule 1, VCAM-1 ELISA Kit

Vascular cell adhesion molecule 1, VCAM-1

Pig Vascular cell adhesion molecule 1; VCAM-1 ELISA Kit; Vascular cell adhesion molecule 1; VCAM-1

vascular cell adhesion protein 1; Vascular cell adhesion protein 1; vascular cell adhesion protein 1; VCAM-1; V-CAM 1; vascular cell adhesion molecule 1; CD_antigen: CD106

VCAM1/CD106

Vcam1; Vcam1; VCAM1B; Vcam-1; V-CAM 1; VCAM-1

VCAM1_RAT

Pig

739

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

Sample Type: serum, plasma, cell culture supernates. Detection Range: 0.78 ng/ml-50 ng/ml. Detection Wavelength: 450 nm. Sensitivity: 0.195 ng/ml

Sample Volume: 50-100ul

Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for VCAM-1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any VCAM-1 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for VCAM-1 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of VCAM-1 bound in the initial step. The color development is stopped and the intensity of the color is measured.

6981700

NP_037021.1

NM_012889.1

P29534

81,246 Da

Adaptive Immune System Pathway 1010925!!African Trypanosomiasis Pathway 194377!!African Trypanosomiasis Pathway 194323!!Cell Adhesion Molecules (CAMs) Pathway 83461!!Cell Adhesion Molecules (CAMs) Pathway 480!!Cytokine Signaling In Immune System Pathway 1011036!!Extracellular Matrix Organization Pathway 1009923!!HTLV-I Infection Pathway 373894!!HTLV-I Infection Pathway 373889!!Immune System Pathway 1010924

binds integrin very late antigen (VLA4); plays a role in cell adhesion [RGD, Feb 2006]

Function: Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation.

96 Strip Wells

915 USD