catalog number :
MBS7050113
products full name :
PLD1 Antibody, FITC conjugated
products short name :
[PLD1]
products name syn :
[Phospholipase D1; PLD 1; hPLD1; Choline phosphatase 1; Phosphatidylcholine-hydrolyzing phospholipase D1; PLD1]
other names :
[phospholipase D1 isoform a; Phospholipase D1; phospholipase D1; phospholipase D1; Choline phosphatase 1; Phosphatidylcholine-hydrolyzing phospholipase D1]
products gene name :
[PLD1]
other gene names :
[PLD1; PLD1; PLD 1; hPLD1]
uniprot entry name :
PLD1_HUMAN
purity :
>95%, Protein G purified
storage stability :
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
tested application :
ELISA (EIA)
other info1 :
Immunogen: Recombinant Human Phospholipase D1 protein (485-627AA). Conjugate: FITC. Storage Buffer: Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, pH 7.4. Species: Homo sapiens (Human). Research Area: Cardiovascular
other info2 :
Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-17847 / sc-17848 / sc-25512 / sc-34316 / sc-48258 / sc-48259
products description :
Implicated as a critical step in numerous cellular pathways, including signal transduction, membrane trafficking, and the regulation of mitosis. May be involved in the regulation of perinuclear intravesicular membrane traffic (By similarity).
ncbi acc num :
NP_002653.1
ncbi gb acc num :
NM_002662.4
ncbi pathways :
Alpha-synuclein Signaling Pathway (137913); Arf6 Downstream Pathway (138038); Arf6 Trafficking Events Pathway (137954); CDC42 Signaling Events Pathway (137994); Choline Metabolism In Cancer Pathway (1059539); Choline Metabolism In Cancer Pathway (1084232); EGF/EGFR Signaling Pathway (198782); Endocytosis Pathway (102279); Endocytosis Pathway (102181); ErbB1 Downstream Signaling Pathway (138057)
ncbi summary :
This gene encodes a phosphatidylcholine-specific phospholipase which catalyzes the hydrolysis of phosphatidylcholine in order to yield phosphatidic acid and choline. The enzyme may play a role in signal transduction and subcellular trafficking. Alternative splicing results in multiple transcript variants with both catalytic and regulatory properties. [provided by RefSeq, Sep 2011]
uniprot summary :
PLD1: a phosphatidylcholine-hydrolyzing phospholipase. Activated by ADP-ribosylated Rho and protein kinase C. Implicated as a critical step in numerous cellular pathways including membrane trafficking and the regulation polymorphonuclear leukocyte degranulation and oxidant production. May be involved in the regulation of perinuclear intravesicular membrane traffic. Four splice-variant isoforms have been described. Protein type: EC 3.1.4.4; Lipid Metabolism - ether lipid; Lipid Metabolism - glycerophospholipid; Motility/polarity/chemotaxis; Phospholipase. Chromosomal Location of Human Ortholog: 3q26. Cellular Component: apical plasma membrane; endocytic vesicle; endoplasmic reticulum membrane; endosome; Golgi apparatus; lysosomal membrane; membrane. Molecular Function: phospholipase D activity; protein binding. Biological Process: cell motility involved in cell locomotion; chemotaxis; phosphatidic acid biosynthetic process; Ras protein signal transduction; regulation of microvillus biogenesis; small GTPase mediated signal transduction