catalog number :
MBS7049999
products full name :
tir Antibody
products short name :
[tir]
products name syn :
[Translocated intimin receptor Tir (Secreted effector protein Tir), tir, espE]
other names :
[translocated intimin receptor Tir; Translocated intimin receptor Tir; Secreted effector protein Tir]
products gene name :
[tir]
other gene names :
[tir; espE]
uniprot entry name :
TIR_ECO5T
reactivity :
Escherichia coli O157:H7
purity :
>95%, Protein G purified
storage stability :
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
tested application :
ELISA (EIA)
other info1 :
Immunogen: Recombinant Escherichia coli O157:H7 Translocated intimin receptor Tir protein (252-362AA)
other info2 :
Storage Buffer: Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, pH 7.4. Conjugate: Non-conjugated. Species: Escherichia coli O157:H7 (strain TW14359 / EHEC). Research Area: Others. Target Names: tir
products description :
Multifunctional protein that is required for efficient pedestal formation in host epithelial cells during infection. The extracellular region acts as a receptor for bacterial intimin, allowing the bacterium to attach tightly to the host-cell surface. Simultaneously, the intracellular region initiates a signaling cascade in the host cell, which leads to actin polymerization and formation of actin pedestals at the sites of bacterial adhesion (By similarity).
ncbi acc num :
WP_001301454.1
ncbi gb acc num :
WP_001301454.1
uniprot summary :
Multifunctional protein that is required for efficient pedestal formation in host epithelial cells during infection. The extracellular region acts as a receptor for bacterial intimin, allowing the bacterium to attach tightly to the host-cell surface. Simultaneously, the intracellular region initiates a signaling cascade in the host cell, which leads to actin polymerization and formation of actin pedestals at the sites of bacterial adhesion ().