Human transthyretin, TTR ELISA Kit | MyBioSource MBS704931 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human transthyretin, TTR ELISA Kit

catalog :

MBS704931

quantity :

24-Strip-Wells (LIMIT 1)

price :

240 USD

more info or order :

MyBioSource product webpage

image

image 1 :

product information

catalog number :

MBS704931

products type :

ELISA Kit

products full name :

Human transthyretin, TTR ELISA Kit

products short name :

[transthyretin]

products name syn :

[Human transthyretin (TTR) ELISA kit; HsT2651; PALB; TBPA; prealbumin; amyloidosis type I; thyroxine-binding prealbumin; transthyretin]

other names :

[transthyretin; Transthyretin; transthyretin; ATTR; carpal tunnel syndrome 1; thyroxine-binding prealbumin; epididymis luminal protein 111; prealbumin, amyloidosis type I; transthyretin; ATTR; Prealbumin; TBPA]

products gene name :

[TTR]

other gene names :

[TTR; TTR; CTS; CTS1; PALB; TBPA; HEL111; HsT2651; PALB]

uniprot entry name :

TTHY_HUMAN

reactivity :

Human

sequence length :

147

specificity :

This assay has high sensitivity and excellent specificity for detection of Human TTR. No significant cross-reactivity or interference between Human TTR and analogues was observed.

storage stability :

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

image1 heading :

Typical Testing Data/Standard Curve (for reference only)

other info1 :

Samples: Serum, plasma, tissue homogenates. Assay Type: Competitive. Detection Range: 1.56 ug/ml-25 ug/ml. Sensitivity: 0.78 ug/ml

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV% is less than 8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV% is less than 10%. Three samples of known concentration were tested in twenty assays to assess. Detection Wavelength: 450 nm. Sample Volume: 50-100ul. Protein Biological Process 1: Transport. Protein Biological Process 3: Transport

products description :

Principle of the Assay: This assay employs the competitive inhibition enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with TTR. Standards or samples are added to the appropriate microtiter plate wells with Horseradish Peroxidase (HRP) conjugated antibody preparation specific for TTR. The competitive inhibition reaction is launched between with pre-coated TTR and TTR in samples. A substrate solution is added to the wells and the color develops in opposite to the amount of TTR in the samples. The color development is stopped and the intensity of the color is measured.

ncbi gi num :

4507725

ncbi acc num :

NP_000362.1

ncbi gb acc num :

NM_000371.3

uniprot acc num :

P02766

ncbi mol weight :

15,887 Da

ncbi pathways :

Amyloids Pathway (366238); Disease Pathway (530764); Diseases Associated With Visual Transduction Pathway (771581); Extracellular Matrix Organization Pathway (576262); FOXA2 And FOXA3 Transcription Factor Networks Pathway (137911); Non-integrin Membrane-ECM Interactions Pathway (833810); Retinoid Cycle Disease Events Pathway (771582); Retinoid Metabolism And Transport Pathway (187208); Signal Transduction Pathway (477114); The Canonical Retinoid Cycle In Rods (twilight Vision) Pathway (771585)

ncbi summary :

This gene encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein; it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc. [provided by RefSeq, Jan 2009]

uniprot summary :

Function: Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.1 PublicationManual assertion based on experiment in:Ref.29

size1 :

24-Strip-Wells (LIMIT 1)

price1 :

240 USD

size2 :

48-Strip-Wells

price2 :

495

size3 :

96-Strip-Wells

price3 :

710

size4 :

5x96-Strip-Wells

price4 :

2705

size5 :

10x96-Strip-Wells

price5 :

5145

more info or order :

MyBioSource product webpage