product summary
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company name :
MyBioSource
product type :
antibody
product name :
IAPP Antibody
catalog :
MBS7048416
quantity :
0.05 mg
price :
160 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
ELISA, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS7048416
products type :
Antibody
products full name :
IAPP Antibody
products short name :
[IAPP]
products name syn :
[Islet amyloid polypeptide; Amylin; Diabetes-associated peptide; DAP; Insulinoma amyloid peptide; IAPP]
other names :
[islet amyloid polypeptide preproprotein; Islet amyloid polypeptide; islet amyloid polypeptide; islet amyloid polypeptide; Amylin; Diabetes-associated peptide; DAP; Insulinoma amyloid peptide]
products gene name :
[IAPP]
other gene names :
[IAPP; IAPP; DAP; IAP; DAP]
uniprot entry name :
IAPP_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human
sequence length :
89
purity :
Caprylic Acid Ammonium Sulfate Precipitation purified
form :
Liquid
storage stability :
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
tested application :
ELISA (EIA)
other info1 :
Immunogen: Recombinant human Islet amyloid polypeptide protein (34-70AA)
other info2 :
Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. Conjugation: Non-conjugated. Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-20936
products description :
Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism.
products references :
1"An islet amyloid peptide is derived from an 89-amino acid precursor by proteolytic processing."Sanke T., Bell G.I., Sample C., Rubenstein A.H., Steiner D.F. J. Biol. Chem. 263: 17243-17246(1988). 2"Cloning and expression of human islet amyloid polypeptide in cultured cells." Bhattacharya S., Naveena Lavanya Latha J., Kumresan R., Singh S. Biochem. Biophys. Res. Commun. 356: 622-628(2007)
ncbi gi num :
4557655
ncbi acc num :
NP_000406.1
ncbi gb acc num :
NM_000415.2
uniprot acc num :
P10997
ncbi mol weight :
9,806 Da
ncbi pathways :
Amyloid Fiber Formation Pathway (1269169); Calcitonin-like Ligand Receptors Pathway (1269571); Class B/2 (Secretin Family Receptors) Pathway (1269570); Developmental Biology Pathway (1270302); G Alpha (s) Signalling Events Pathway (1269575); GPCR Downstream Signaling Pathway (1269574); GPCR Ligand Binding Pathway (1269544); Integrated Pancreatic Cancer Pathway (711360); Maturity Onset Diabetes Of The Young Pathway (83096); Maturity Onset Diabetes Of The Young Pathway (508)
ncbi summary :
This gene encodes a member of the calcitonin family of peptide hormones. This hormone is released from pancreatic beta cells following food intake to regulate blood glucose levels and act as a satiation signal. Human patients with type 1 and advanced type 2 diabetes exhibit reduced levels of the encoded hormone in blood and pancreas. This protein also exhibits a bactericidal, antimicrobial activity. [provided by RefSeq, Jul 2016]
uniprot summary :
IAPP: Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism. Belongs to the calcitonin family. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 12p12.1. Cellular Component: extracellular region. Molecular Function: identical protein binding; receptor binding. Biological Process: apoptosis; cell-cell signaling; cellular protein metabolic process; signal transduction
size1 :
0.05 mg
price1 :
160 USD
size2 :
0.1 mg
price2 :
235
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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