product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Rat anti-Thyroid-Peroxidase antibody, TPO-Ab ELISA Kit
catalog :
MBS704812
quantity :
48-Strip-Wells
price :
605 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS704812
products type :
ELISA Kit
products full name :
Rat anti-Thyroid-Peroxidase antibody, TPO-Ab ELISA Kit
products short name :
anti-Thyroid-Peroxidase antibody, TPO-Ab
products name syn :
Rat anti-Thyroid-Peroxidase antibody; TPO-Ab ELISA Kit; anti-Thyroid-Peroxidase antibody; TPO-Ab
other names :
thyroid peroxidase isoform b; Thyroid peroxidase; thyroid peroxidase; thyroperoxidase; thyroid microsomal antigen; thyroid peroxidase
other gene names :
TPO; TPO; MSA; TPX; TDH2A; TPO
uniprot entry name :
PERT_HUMAN
reactivity :
Rat
sequence length :
876
storage stability :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
other info1 :
Samples: Serum, plasma, tissue homogenates. Assay Type: Competitive. Detection Range: 5 IU/ml-80 IU/ml. Sensitivity: 2.5 IU/ml
other info2 :
Detection Wavelength: 450 nm. Sample Volume: 50-100ul
products description :
Principle of the Assay: This assay employs the competitive inhibition enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with antigen. Standards or samples are added to the appropriate microtiter plate wells with biotin-conjugated anti-TPO antibody. A competitive inhibition reaction is launched between anti-TPO antibody (Standards or samples) and Biotin-conjugated anti-TPO antibody with the pre-coated antigen. The more amount of anti-TPO antibody in samples, the less pre-coated antigen bound by Biotin-conjugated anti-TPO antibody. After washing, Horseradish Peroxidase (HRP)-conjugated avidin is added to the wells. Substrate solution is added to the wells and the color develops in opposite to the amount of anti-TPO antibody in the sample. The color development is stopped and the intensity of the color is measured.
ncbi gi num :
332078492
ncbi acc num :
NP_001193674.1
ncbi gb acc num :
NM_001206745.1
uniprot acc num :
P07202
ncbi mol weight :
92,063 Da
ncbi pathways :
Amine-derived Hormones Pathway (160983); Autoimmune Thyroid Disease Pathway (83121); Autoimmune Thyroid Disease Pathway (533); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); Hematopoietic Cell Lineage Pathway (83078); Hematopoietic Cell Lineage Pathway (489); Jak-STAT Signaling Pathway (83077); Jak-STAT Signaling Pathway (488); Metabolic Pathways (132956)
ncbi summary :
This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2011]
uniprot summary :
Function: Iodination and coupling of the hormonogenic tyrosines in thyroglobulin to yield the thyroid hormones T3 and T4. Catalytic activity: 2 iodide + H2O2 + 2 H+ = 2 iodine + 2 H2O. Cofactor: Binds 1 calcium ion per heterodimer
size1 :
48-Strip-Wells
price1 :
605 USD
size2 :
96-Strip-Wells
price2 :
870
size3 :
5x96-Strip-Wells
price3 :
2950
size4 :
10x96-Strip-Wells
price4 :
5535
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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