catalog number :
MBS704811
products type :
ELISA Kit
products full name :
Mouse Calcitonin, CT ELISA Kit
products short name :
calcitonin-related polypeptide alpha
products name syn :
Mouse Calcitonin; CT ELISA Kit; CALC1; CGRP; CGRP-I; CGRP1; CT; KC; MGC126648; calcitonin 1; calcitonin gene-related peptide 1; calcitonin/calcitonin-related polypeptide; alpha; katacalcin; calcitonin-related polypeptide alpha
other names :
calcitonin gene-related peptide 1 isoform Cgrp preproprotein; Calcitonin gene-related peptide 1; calcitonin gene-related peptide 1; alpha CGRP; alpha-type CGRP; calcitonin gene-related peptide I; calcitonin/calcitonin-related polypeptide, alpha; Alpha-type CGRP; Calcitonin gene-related peptide I; CGRP-I
products gene name :
CALCA
other gene names :
Calca; Calca; CA; Ct; Ctn; Calc; Cgrp; CGRP1; Calc1; CGRP-1; Calc; CGRP-I
uniprot entry name :
CALCA_MOUSE
specificity :
This assay has high sensitivity and excellent specificity for detection of Mouse CALCA. No significant cross-reactivity or interference between Mouse CALCA and analogues was observed.
storage stability :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
other info1 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV% is less than 8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV% is less than 10%. Three samples of known concentration were tested in twenty assays to assess. Sample Type: serum, plasma, cell culture supernates, tissue homogenates. Detection Range: 12.5 pg/ml-800 pg/ml. Detection Wavelength: 450 nm. Sensitivity: 3.125pg/ml
other info2 :
Sample Volume: 50-100ul
products description :
Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for CT has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any CT present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for CT is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of CT bound in the initial step. The color development is stopped and the intensity of the color is measured.
ncbi acc num :
NP_001029126.1
ncbi gb acc num :
NM_001033954.3
ncbi mol weight :
14,065 Da
ncbi pathways :
Amyloids Pathway 1000612!!Calcitonin-like Ligand Receptors Pathway 1000968!!Class B/2 (Secretin Family Receptors) Pathway 1000967!!Disease Pathway 970606!!G Alpha (s) Signalling Events Pathway 1000972!!GPCR Downstream Signaling Pathway 1000971!!GPCR Ligand Binding Pathway 1000941!!Myometrial Relaxation And Contraction Pathways 198333!!Signal Transduction Pathway 970540!!Signaling By GPCR Pathway 971377
uniprot summary :
Function: CGRP induces vasodilation. It dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role. It also elevates platelet cAMP