CD96 Antibody | MyBioSource MBS7047861 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

CD96 Antibody

catalog :

MBS7047861

quantity :

0.05 mg

price :

160 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human

application :

ELISA, immunohistochemistry, immunocytochemistry, enzyme immunoassay

more info or order :

MyBioSource product webpage

image

image 1 :

Immunohistochemistry of paraffin-embedded human lung tissue using MBS7047861 at dilution of 1:100

image 2 :

Immunofluorescent analysis of HepG2 cells using MBS7047861 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

image 3 :

Western Blot. Positive WB detected in: HepG2 whole cell lysate,Jurkat whole cell lysate,HEK293 whole cell lysate. All lanes: CD96 antibody at 2.5ug/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 66,64 KDa. Observed band size: 66 KDa.

product information

catalog number :

MBS7047861

products type :

Antibody

products full name :

CD96 Antibody

products short name :

[CD96]

products name syn :

[T-cell surface protein tactile; Cell surface antigen CD96; T cell-activated increased late expression protein; CD96; CD96]

other names :

[T-cell surface protein tactile isoform 2; T-cell surface protein tactile; T-cell surface protein tactile; CD96 molecule; Cell surface antigen CD96; T cell-activated increased late expression protein; CD_antigen: CD96]

products gene name :

[CD96]

other gene names :

[CD96; CD96; TACTILE]

uniprot entry name :

TACT_HUMAN

clonality :

Polyclonal

isotype :

IgG

host :

Rabbit

reactivity :

Human

sequence length :

569

purity :

>95%, Protein G purified

form :

Liquid

storage stability :

Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

tested application :

ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF)

app notes :

IHC: 1: 20-1: 200. IF: 1: 50-1: 200

image1 heading :

Immunohistochemistry (IHC)

image2 heading :

Immunofluorescence (IF)

image3 heading :

Western Blot (WB)

other info1 :

Immunogen: Recombinant Human T-cell surface protein tactile protein (306-395AA)

other info2 :

Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. Conjugation: Non-conjugated

products description :

May be involved in adhesive interactions of activated T and NK cells during the late phase of the immune response. Promotes NK cell-target adhesion by interacting with PVR present on target cells. May function at a time after T and NK cells have penetrated the endothelium using integrins and selectins, when they are actively engaging diseased cells and moving within areas of inflammation.

ncbi gi num :

5032141

ncbi acc num :

NP_005807.1

ncbi gb acc num :

NM_005816.4

uniprot acc num :

P40200

ncbi mol weight :

63,888 Da

ncbi pathways :

Adaptive Immune System Pathway (1269171); Immune System Pathway (1269170); Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway (1269201)

ncbi summary :

The protein encoded by this gene belongs to the immunoglobulin superfamily. It is a type I membrane protein. The protein may play a role in the adhesive interactions of activated T and NK cells during the late phase of the immune response. It may also function in antigen presentation. Alternative splicing generates multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2016]

uniprot summary :

CD96: May be involved in adhesive interactions of activated T and NK cells during the late phase of the immune response. Promotes NK cell-target adhesion by interacting with PVR present on target cells. May function at a time after T and NK cells have penetrated the endothelium using integrins and selectins, when they are actively engaging diseased cells and moving within areas of inflammation. Defects in CD96 are a cause of C syndrome (CSYN); also called Opitz trigonocephaly syndrome. This syndrome is characterized by trigonocephaly and associated anomalies, such as unusual facies, wide alveolar ridges, multiple buccal frenula, limb defects, visceral anomalies, redundant skin, psychomotor retardation and hypotonia. A chromosomal aberration involving CD96 has been found in a patient with C syndrome. Translocation t(3;18)(q13.13;q12.1). CD96 gene was located at the 3q13.13 breakpoint. Precise structural analysis around the breakpoint showed that the gene was disrupted by the translocation in exon 5, probably leading to premature termination or loss of expression of CD96 protein. No gene was detected at the chromosome 18 breakpoint. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Cell adhesion; Membrane protein, integral. Chromosomal Location of Human Ortholog: 3q13.13-q13.2. Cellular Component: adherens junction; cytoplasm; integral to plasma membrane; plasma membrane. Biological Process: cell adhesion; cell-matrix adhesion; immune response; regulation of immune response. Disease: C Syndrome

size1 :

0.05 mg

price1 :

160 USD

size2 :

0.1 mg

price2 :

235

more info or order :

MyBioSource product webpage