Human Soluble Cluster of differentiation 38, sCD38 ELISA Kit | MyBioSource MBS704723 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human Soluble Cluster of differentiation 38, sCD38 ELISA Kit

catalog :

MBS704723

quantity :

48-Strip-Wells

price :

510 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS704723

products type :

ELISA Kit

products full name :

Human Soluble Cluster of differentiation 38, sCD38 ELISA Kit

products short name :

CD38 molecule

products name syn :

Human Soluble Cluster of differentiation 38; sCD38 ELISA Kit; T10; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase; CD38 antigen; CD38 antigen (p45) ; cyclic ADP-ribose hydrolase; CD38 molecule

other names :

ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; cADPr hydrolase 1; CD38 antigen (p45); NAD(+) nucleosidase; ADP-ribosyl cyclase 1; 2'-phospho-ADP-ribosyl cyclase; 2'-phospho-cyclic-ADP-ribose transferase; 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase; CD38 molecule; 2'-phospho-ADP-ribosyl cyclase; 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase (EC:2.4.99.20); 2'-phospho-cyclic-ADP-ribose transferase; ADP-ribosyl cyclase 1; ADPRC 1; Cyclic ADP-ribose hydrolase 1; cADPr hydrolase 1; T10; CD_antigen: CD38

products gene name :

CD38

other gene names :

CD38; CD38; T10; ADPRC 1; ADPRC 1; cADPr hydrolase 1

uniprot entry name :

CD38_HUMAN

reactivity :

Human

sequence length :

300

specificity :

This assay has high sensitivity and excellent specificity for detection of human sCD38. No significant cross-reactivity or interference between human sCD38 and analogues was observed.

storage stability :

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

other info1 :

Samples: Serum, plasma, tissue homogenates and Cell lysates Cell lysates Cell lysates Cell lysates Cell lysates Cell lysates Cell lysates Cell lysates Cell lysates Cell lysates Cell lysates Cell lysates. Assay Type: Sandwich. Detection Range: 0.9 ng/ml -60 ng/ml. Sensitivity: The minimum detectable dose of human sCD38 is typically less than 0.225 ng/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations.

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.

products description :

Principle of the assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for sCD38 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any sCD38 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for sCD38 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of sCD38 bound in the initial step. The color development is stopped and the intensity of the color is measured.

ncbi gi num :

38454326

ncbi acc num :

NP_001766.2

ncbi gb acc num :

NM_001775.2

uniprot acc num :

P28907

ncbi mol weight :

34,328 Da

ncbi pathways :

Calcium Signaling Pathway (83050); Calcium Signaling Pathway (459); Epstein-Barr Virus Infection Pathway (585562); Epstein-Barr Virus Infection Pathway (587115); Hematopoietic Cell Lineage Pathway (83078); Hematopoietic Cell Lineage Pathway (489); Metabolic Pathways (132956); Nicotinate And Nicotinamide Metabolism Pathway (83014); Nicotinate And Nicotinamide Metabolism Pathway (400); Oxytocin Signaling Pathway (952859)

ncbi summary :

CD38 is a novel multifunctional ectoenzyme widely expressed in cells and tissues especially in leukocytes. CD38 also functions in cell adhesion,signal transduction and calcium signaling. [provided by RefSeq, Jul 2008]

uniprot summary :

Function: Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system. Catalytic activity: NAD+ + H2O = ADP-D-ribose + nicotinamide.1 PublicationManual assertion based on experiment in:Ref.8. Enzyme regulation: ATP inhibits the hydrolyzing activity.

size1 :

48-Strip-Wells

price1 :

510 USD

size2 :

96-Strip-Wells

price2 :

725

size3 :

5x96-Strip-Wells

price3 :

2565

size4 :

10x96-Strip-Wells

price4 :

4800

more info or order :

MyBioSource product webpage