product summary
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company name :
MyBioSource
product type :
antibody
product name :
ACOD1 Antibody
catalog :
MBS7046180
quantity :
0.05 mg
price :
160 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
image
image 1 :
Immunohistochemistry of paraffin-embedded human glioma cancer using MBS7046180 at dilution of 1:100
image 2 :
Immunohistochemistry of paraffin-embedded human appendix tissue using MBS7046180 at dilution of 1:100
product information
catalog number :
MBS7046180
products type :
Antibody
products full name :
ACOD1 Antibody
products short name :
[ACOD1]
products name syn :
[Cis-aconitate decarboxylase; Aconitate decarboxylase; Aconitate decarboxylase; ACOD1]
other names :
[cis-aconitate decarboxylase; Cis-aconitate decarboxylase; cis-aconitate decarboxylase; aconitate decarboxylase 1; Aconitate decarboxylase; Aconitate decarboxylase 1]
products gene name :
[ACOD1]
other gene names :
[ACOD1; ACOD1; CAD; IRG1; CAD]
uniprot entry name :
IRG1_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human
sequence length :
481
purity :
>95%, Protein G purified
form :
Liquid
storage stability :
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
tested application :
ELISA (EIA), Immunohistochemistry (IHC)
image1 heading :
Immunohistochemistry (IHC)
image2 heading :
Immunohistochemistry (IHC)
other info1 :
Species: Human. Immunogen: Recombinant human Cis-aconitate decarboxylase protein
other info2 :
Conjugate: Non-conjugated. Buffer: Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
products description :
Involved in the inhibition of the inflammatory response. Acts as a negative regulator of the Toll-like receptors (TLRs)-mediated inflammatory innate response by stimulating the tumor necrosis factor alpha-induced protein TNFAIP3 expression via reactive oxygen species (ROS) in LPS-tolerized macrophages. Involved in antimicrobial response of innate immune cells; ACOD1-mediated itaconic acid production contributes to the antimicrobial activity of macrophages. Plays a role in the embryo implantation.
ncbi gi num :
385719224
ncbi acc num :
NP_001245335.1
ncbi gb acc num :
NM_001258406.1
uniprot acc num :
A6NK06
ncbi mol weight :
52,628 Da
uniprot summary :
IRG1: Belongs to the PrpD family. Protein type: EC 4.1.1.6. Chromosomal Location of Human Ortholog: 13q22.3. Cellular Component: mitochondrion. Molecular Function: aconitate decarboxylase activity. Biological Process: defense response; embryo implantation; inhibition of NF-kappaB transcription factor; metabolic process; negative regulation of inflammatory response; negative regulation of innate immune response; negative regulation of interferon type I production; negative regulation of toll-like receptor 2 signaling pathway; negative regulation of toll-like receptor 4 signaling pathway; positive regulation of antimicrobial humoral response
size1 :
0.05 mg
price1 :
160 USD
size2 :
0.1 mg
price2 :
235
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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