catalog number :
MBS7046048
products full name :
BTNL2 Antibody
products short name :
[BTNL2]
products name syn :
[Butyrophilin-like protein 2; BTL-II; BTNL2]
other names :
[butyrophilin-like protein 2; Butyrophilin-like protein 2; butyrophilin-like protein 2; butyrophilin like 2]
products gene name :
[BTNL2]
other gene names :
[BTNL2; BTNL2; SS2; BTN7; BTL-II; HSBLMHC1; BTL-II]
uniprot entry name :
BTNL2_HUMAN
reactivity :
Human, Mouse
purity :
>95%, Protein G purified
storage stability :
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
Recommended Dilution: WB: 1:2000-1:10000, IHC: 1:20-1:200
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
image3 heading :
Immunohistochemistry (IHC)
other info1 :
Immunogen: Recombinant human Butyrophilin-like protein 2 protein (26-202AA)
other info2 :
Conjugate: Non-conjugated. Buffer: Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. Species: Human. Research Area: Immunology. Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-167237
products description :
Negative regulator of T-cell proliferation.
ncbi acc num :
NP_001291490.1
ncbi gb acc num :
NM_001304561.1
uniprot summary :
BTNL2: Negative regulator of T-cell proliferation. Genetic variation in BTNL2 is a cause of susceptibility to sarcoidosis type 2 (SS2). Sarcoidosis is an idiopathic, systemic, inflammatory disease characterized by the formation of immune granulomas in involved organs. Granulomas predominantly invade the lungs and the lymphatic system, but also skin, liver, spleen, eyes and other organs may be involved. A nucleotide transition affecting a splice donor site results in the use of an alternative splice site and the production of isoform 3. Individuals expressing isoform 3 have a higher risk for sarcoidosis. Belongs to the immunoglobulin superfamily. BTN/MOG family. 6 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: 6p21.3. Disease: Sarcoidosis, Susceptibility To, 2