catalog number :
MBS704604
products type :
ELISA Kit
products full name :
Rat Urokinase-type Plasminogen Activator Receptor, PLAUR/uPAR ELISA Kit
products short name :
plasminogen activator, urokinase receptor
products name syn :
Rat Urokinase-type Plasminogen Activator Receptor; PLAUR/uPAR ELISA kit; CD87; UPAR; URKR; monocyte activation antigen Mo3; u-plasminogen activator receptor form 2; plasminogen activator; urokinase receptor
other names :
urokinase plasminogen activator surface receptor isoform 2; Urokinase plasminogen activator surface receptor; urokinase plasminogen activator surface receptor; U-PAR; urinary plasminogen activator receptor 2; urinary plasminogen activator receptor 3; urokinase plasminogen activator receptor; plasminogen activator urokinase receptor 3; plasminogen activator, urokinase receptor; CD_antigen: CD87
products gene name :
PLAUR
other gene names :
Plaur; Plaur; Par; uPAR; Plaur3; uPAR-2; uPAR-3; U-PAR; uPAR
uniprot entry name :
UPAR_RAT
specificity :
This assay has high sensitivity and excellent specificity for detection of Rat PLAUR. No significant cross-reactivity or interference between Rat PLAUR and analogues was observed.
storage stability :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
other info1 :
Samples: Serum, plasma, tissue homogenates. Assay Type: Sandwich. Detection Range: 0.156 ng/ml-10 ng/ml. Sensitivity: 0.039 ng/ml
other info2 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV% is less than 8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV% is less than 10%. Three samples of known concentration were tested in twenty assays to assess. Detection Wavelength: 450 nm. Sample Volume: 50-100ul
products description :
Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for PLAUR has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any PLAUR present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for PLAUR is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of PLAUR bound in the initial step. The color development is stopped and the intensity of the color is measured.
ncbi acc num :
NP_059046.1
ncbi gb acc num :
NM_017350.1
ncbi mol weight :
35,753 Da
ncbi pathways :
Complement And Coagulation Cascades Pathway (198461); Complement And Coagulation Cascades Pathway (83465); Complement And Coagulation Cascades Pathway (484); Proteoglycans In Cancer Pathway (782034); Proteoglycans In Cancer Pathway (782054)
ncbi summary :
receptor for urokinase-plasminogen activator; may play a central role in malignant tumour progression [RGD, Feb 2006]
uniprot summary :
Function: Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA.
size4 :
10x96-Strip-Wells