product summary
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company name :
MyBioSource
product type :
antibody
product name :
HK3 Antibody
catalog :
MBS7045756
quantity :
0.05 mL
price :
120 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
image
image 1 :
Western blot. All lanes: HK3 antibody at 1.47 ug/ml. Lane 1: Mouse liver tissue. Lane 2: Mouse kidney tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 99 kDa. Observed band size: 99 kDa.
image 2 :
Immunohistochemistry of paraffin-embedded human lung cancer using MBS7045756 at dilution of 1:100
image 3 :
Immunohistochemistry of paraffin-embedded human spleen tissue using MBS7045756 at dilution of 1:100
product information
catalog number :
MBS7045756
products type :
Antibody
products full name :
HK3 Antibody
products short name :
[HK3]
products name syn :
[Hexokinase-3 (EC 2.7.1.1) (Hexokinase type III) (HK III), HK3]
other names :
[hexokinase-3; Hexokinase-3; hexokinase-3; hexokinase 3; Hexokinase type III; HK III]
products gene name :
[HK3]
other gene names :
[HK3; HK3; HXK3; HKIII; HK III]
uniprot entry name :
HXK3_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse
purity :
Antigen Affinity Purified
form :
Liquid
storage stability :
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
Recommended dilution: . WB: 1:1000-1:5000. IHC: 1:20-1:200
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
image3 heading :
Immunohistochemistry (IHC)
other info1 :
Immunogen: Recombinant Human Hexokinase-3 protein (1-270AA). Conjugate: Non-conjugated. Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Species: Human. Research Area: Signal Transduction
other info2 :
Conjugate: Non-conjugated. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-6523 / sc-28890. Species: Human. Research Area: Signal Transduction. Target Names: HK3
products description :
cytosol, fructokinase activity, glucokinase activity, hexokinase activity, mannokinase activity, canonical glycolysis, cellular glucose homeostasis, glucose transport, glycolytic process
ncbi gi num :
194097330
ncbi acc num :
NP_002106.2
ncbi gb acc num :
NM_002115.2
uniprot acc num :
P52790
ncbi pathways :
Amino Sugar And Nucleotide Sugar Metabolism Pathway (82979); Amino Sugar And Nucleotide Sugar Metabolism Pathway (350); Butirosin And Neomycin Biosynthesis Pathway (145809); Butirosin And Neomycin Biosynthesis Pathway (145786); Carbohydrate Digestion And Absorption Pathway (170720); Carbohydrate Digestion And Absorption Pathway (170654); Carbon Metabolism Pathway (814926); Carbon Metabolism Pathway (817567); Central Carbon Metabolism In Cancer Pathway (1059538); Central Carbon Metabolism In Cancer Pathway (1084231)
ncbi summary :
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 3. Similar to hexokinases 1 and 2, this allosteric enzyme is inhibited by its product glucose-6-phosphate. [provided by RefSeq, Apr 2009]
uniprot summary :
HK3: a glycolytic enzyme that catalyzes the reaction ATP + D-hexose = ADP + D-hexose 6-phosphate. The first and rate-limiting step in glycosis, a pathway that produces energy in the form of ATP from glucose. An allosteric enzyme inhibited by its product glucose-6-phosphate (Glc-6-P). Acts as a glucose sensor by trapping glucose inside the cell by catalyzing its phosphorylation to produce Glc-6-P. In vertebrates there are four major glucose-phosphorylating isoenzymes, designated hexokinase I, II, III and IV (glucokinase). Protein type: Enzyme, cellular metabolism; Carbohydrate Metabolism - amino sugar and nucleotide sugar; Transferase; Carbohydrate Metabolism - fructose and mannose; Carbohydrate Metabolism - starch and sucrose; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Carbohydrate Metabolism - galactose; EC 2.7.1.1; Kinase, other. Chromosomal Location of Human Ortholog: 5q35.2. Cellular Component: cytosol. Molecular Function: fructokinase activity; glucokinase activity; hexokinase activity; mannokinase activity. Biological Process: cell glucose homeostasis; glucose transport; glycolysis
size1 :
0.05 mL
price1 :
120 USD
size2 :
0.1 mL
price2 :
160
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
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