product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Human acidic fibroblast growth factor, aFGF/FGF-1 ELISA Kit
catalog :
MBS704562
quantity :
48-Strip-Wells
price :
435 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS704562
products type :
ELISA Kit
products full name :
Human acidic fibroblast growth factor, aFGF/FGF-1 ELISA Kit
products short name :
fibroblast growth factor 1 (acidic)
products name syn :
Human acidic fibroblast growth factor; aFGF/FGF-1 ELISA Kit; AFGF; ECGF; ECGF-beta; ECGFA; ECGFB; FGF-alpha; FGFA; GLIO703; HBGF1; OTTHUMP00000066031; endothelial cell growth factor; alpha; endothelial cell growth factor; beta; heparin-binding growth factor 1; fibroblast growth factor 1 (acidic)
other names :
fibroblast growth factor 1 isoform 1; Fibroblast growth factor 1; fibroblast growth factor 1; heparin-binding growth factor 1; beta-endothelial cell growth factor; endothelial cell growth factor, beta; endothelial cell growth factor, alpha; fibroblast growth factor 1 (acidic); Acidic fibroblast growth factor; aFGF; Endothelial cell growth factor; ECGF; Heparin-binding growth factor 1; HBGF-1
products gene name :
FGF1
other gene names :
FGF1; FGF1; AFGF; ECGF; FGFA; ECGFA; ECGFB; FGF-1; HBGF1; HBGF-1; GLIO703; ECGF-beta; FGF-alpha; FGFA; FGF-1; aFGF; ECGF; HBGF-1
uniprot entry name :
FGF1_HUMAN
reactivity :
Human
sequence length :
155
specificity :
This assay has high sensitivity and excellent specificity for detection of human aFGF. No significant cross-reactivity or interference between human aFGF and analogues was observed.
storage stability :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
other info1 :
Samples: Serum, plasma, tissue homogenates. Assay Type: Sandwich. Detection Range: 15.6 pg/ml -1000 pg/ml. Sensitivity: Typically less than 3.9 pg/ml
other info2 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
products description :
Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for aFGF has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any aFGF present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for aFGF is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of aFGF bound in the initial step. The color development is stopped and the intensity of the color is measured.
ncbi gi num :
4503697
ncbi acc num :
NP_000791.1
ncbi gb acc num :
NM_000800.4
uniprot acc num :
P05230
ncbi mol weight :
17,460 Da
ncbi pathways :
Activated Point Mutants Of FGFR2 Pathway (645281); Adaptive Immune System Pathway (366160); Constitutive PI3K/AKT Signaling In Cancer Pathway (685535); DAP12 Interactions Pathway (685549); DAP12 Signaling Pathway (685550); Disease Pathway (530764); Downstream Signal Transduction Pathway (106385); Downstream Signaling Events Of B Cell Receptor (BCR) Pathway (576250); Downstream Signaling Of Activated FGFR Pathway (160957); FGF Signaling Pathway (137989)
ncbi summary :
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Multiple alternatively spliced variants encoding different isoforms have been described. [provided by RefSeq, Jan 2009]
uniprot summary :
Function: Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro.3 PublicationsManual assertion based on experiment in:Ref.20
size1 :
48-Strip-Wells
price1 :
435 USD
size2 :
96-Strip-Wells
price2 :
615
size3 :
5x96-Strip-Wells
price3 :
2340
size4 :
10x96-Strip-Wells
price4 :
4370
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

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