Human heparin-binding epidermal growth factor-like growth factor, HB-EGF ELISA Kit | MyBioSource MBS704504 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human heparin-binding epidermal growth factor-like growth factor, HB-EGF ELISA Kit

catalog :

MBS704504

quantity :

48-Strip-Wells

price :

510 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS704504

products type :

ELISA Kit

products full name :

Human heparin-binding epidermal growth factor-like growth factor, HB-EGF ELISA Kit

products short name :

heparin-binding EGF-like growth factor

products name syn :

Human heparin-binding epidermal growth factor-like growth factor; HB-EGF ELISA Kit; DTR; DTS; DTSF; HEGFL; diphtheria toxin receptor (heparin-binding EGF-like growth factor) ; diphtheria toxin receptor (heparin-binding epidermal growth factor-like growth factor) ; heparin-binding epide; heparin-binding EGF-like growth factor

other names :

proheparin-binding EGF-like growth factor; Proheparin-binding EGF-like growth factor; proheparin-binding EGF-like growth factor; heparin-binding epidermal growth factor; diphtheria toxin receptor (heparin-binding EGF-like growth factor); diphtheria toxin receptor (heparin-binding epidermal growth factor-like growth factor); heparin-binding EGF-like growth factor; Diphtheria toxin receptor; DT-R

products gene name :

HBEGF

other gene names :

HBEGF; HBEGF; DTR; DTS; DTSF; HEGFL; DTR; DTS; HEGFL; HB-EGF; HBEGF; DT-R

uniprot entry name :

HBEGF_HUMAN

reactivity :

Human

sequence length :

208

specificity :

This assay has high sensitivity and excellent specificity for detection of Human HBEGF. No significant cross-reactivity or interference between Human HBEGF and analogues was observed.

storage stability :

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

other info1 :

Samples: Serum, plasma, tissue homogenates. Assay Type: Sandwich. Detection Range: 62.5 pg/ml-4000 pg/ml. Sensitivity: 15.6 pg/ml

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV% is less than 8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV% is less than 10%. Three samples of known concentration were tested in twenty assays to assess. Detection Wavelength: 450 nm. Sample Volume: 50-100ul

products description :

Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for HB-EGF has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any HB-EGF present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for HB-EGF is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of HB-EGF bound in the initial step. The color development is stopped and the intensity of the color is measured.

ncbi gi num :

4503413

ncbi acc num :

NP_001936.1

ncbi gb acc num :

NM_001945.2

uniprot acc num :

Q99075

ncbi mol weight :

23,067 Da

ncbi pathways :

Adaptive Immune System Pathway (366160); Constitutive PI3K/AKT Signaling In Cancer Pathway (685535); DAP12 Interactions Pathway (685549); DAP12 Signaling Pathway (685550); Disease Pathway (530764); Downstream Signal Transduction Pathway (106385); Downstream Signaling Events Of B Cell Receptor (BCR) Pathway (576250); Downstream Signaling Of Activated FGFR Pathway (160957); EGFR Transactivation By Gastrin Pathway (645296); Epithelial Cell Signaling In Helicobacter Pylori Infection Pathway (83102)

uniprot summary :

Function: Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.

size1 :

48-Strip-Wells

price1 :

510 USD

size2 :

96-Strip-Wells

price2 :

725

size3 :

5x96-Strip-Wells

price3 :

2565

size4 :

10x96-Strip-Wells

price4 :

4800

more info or order :

MyBioSource product webpage