product summary
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company name :
MyBioSource
product type :
antibody
product name :
SLC22A8 Antibody
catalog :
MBS7044950
quantity :
0.05 mL
price :
120 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
more info or order :
image
image 1 :
Western blot. All lanes: SLC22A8antibody IgG at 1.62ug/ml+ Mouse kidney tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 60,61,47,12,50 kDa. Observed band size: 60 kDa.
image 2 :
Immunohistochemistry of paraffin-embedded human kidney tissue MBS7044950 at dilution 1:100
image 3 :
Immunohistochemistry of paraffin-embedded human adrenal gland tissue MBS7044950 at dilution 1:100
product information
catalog number :
MBS7044950
products type :
Antibody
products full name :
SLC22A8 Antibody
products short name :
[SLC22A8]
products name syn :
[Solute carrier family 22 member 8; Organic anion transporter 3; hOAT3; SLC22A8; OAT3]
other names :
[solute carrier family 22 member 8 isoform 1; Solute carrier family 22 member 8; solute carrier family 22 member 8; solute carrier family 22 member 8; Organic anion transporter 3; hOAT3]
products gene name :
[SLC22A8]
other gene names :
[SLC22A8; SLC22A8; OAT3; OAT3; hOAT3]
uniprot entry name :
S22A8_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse
sequence length :
542
purity :
Antigen Affinity Purified
form :
Liquid
storage stability :
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
Recommended dilution: WB: 1:1000-1:5000, IHC: 1:20-1:200
image1 heading :
Western Blot (WB)
image2 heading :
Immunohistochemistry (IHC)
image3 heading :
Immunohistochemistry (IHC)
other info1 :
Species: Human. Immunogen: Recombinant human Solute carrier family 22 member 8 protein (473-542AA). Research Area: Signal Transduction
other info2 :
Conjugate: Non-conjugated. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-107836
products description :
Plays an important role in the excretion/detoxification of endogenous and exogenous organic anions, especially from the brain and kidney. Involved in the transport basolateral of steviol, fexofenadine. Transports benzylpenicillin (PCG), estrone-3-sulfate (E1S), cimetidine (CMD), 2,4-dichloro-phenoxyacetate (2,4-D), p-amino-hippurate (PAH), acyclovir (ACV) and ochratoxin (OTA).
ncbi gi num :
296080719
ncbi acc num :
NP_001171661.1
ncbi gb acc num :
NM_001184732.1
uniprot acc num :
Q8TCC7
ncbi pathways :
Bile Secretion Pathway (193146); Bile Secretion Pathway (193095); Organic Anion Transport Pathway (1269938); Organic Cation/anion/zwitterion Transport Pathway (1269936); SLC-mediated Transmembrane Transport Pathway (1269907); Transmembrane Transport Of Small Molecules Pathway (1269903); Transport Of Glucose And Other Sugars, Bile Salts And Organic Acids, Metal Ions And Amine Compounds Pathway (1269923)
ncbi summary :
This gene encodes a protein involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and appears to be localized to the basolateral membrane of the kidney. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, May 2010]
uniprot summary :
SLC22A8: Plays an important role in the excretion/detoxification of endogenous and exogenous organic anions, especially from the brain and kidney. Involved in the transport basolateral of steviol, fexofenadine. Transports benzylpenicillin (PCG), estrone- 3-sulfate (E1S), cimetidine (CMD), 2,4-dichloro-phenoxyacetate (2,4-D), p-amino-hippurate (PAH), acyclovir (ACV) and ochratoxin (OTA). Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Transporter; Membrane protein, integral; Membrane protein, multi-pass; Transporter, SLC family. Chromosomal Location of Human Ortholog: 11q11. Cellular Component: basolateral plasma membrane; integral to plasma membrane; plasma membrane. Molecular Function: anion:anion antiporter activity; inorganic anion exchanger activity; sodium-independent organic anion transmembrane transporter activity. Biological Process: sodium-independent organic anion transport
size1 :
0.05 mL
price1 :
120 USD
size2 :
0.1 mL
price2 :
160
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
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