product summary
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company name :
MyBioSource
product type :
antibody
product name :
MYO1G Antibody
catalog :
MBS7044904
quantity :
0.05 mg
price :
160 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
ELISA, immunohistochemistry, immunocytochemistry, enzyme immunoassay
more info or order :
image
image 1 :
Immunohistochemistry of paraffin-embedded human lymphoid tissue using MBS7044904 at dilution of 1:100
image 2 :
Immunohistochemistry of paraffin-embedded human appendix tissue using MBS7044904 at dilution of 1:100
image 3 :
Immunofluorescent analysis of HepG2 cells using MBS7044904 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
product information
catalog number :
MBS7044904
products type :
Antibody
products full name :
MYO1G Antibody
products short name :
[MYO1G]
products name syn :
[Unconventional myosin-Ig [Cleaved into: Minor histocompatibility antigen HA-2 (mHag HA-2)], MYO1G, HA2]
other names :
[unconventional myosin-Ig; Unconventional myosin-Ig; unconventional myosin-Ig; myosin IG]
products gene name :
[MYO1G]
other gene names :
[MYO1G; MYO1G; HA2; MHAG; HLA-HA2; HA2; mHag HA-2]
uniprot entry name :
MYO1G_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human
purity :
>95%, Protein G purified
form :
Liquid
storage stability :
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
tested application :
ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF)
app notes :
IHC:1:20-1:200. IF:1:50-1:200
image1 heading :
Immunohistochemistry (IHC)
image2 heading :
Immunohistochemistry (IHC)
image3 heading :
Immunofluorescent (IF)
other info1 :
Immunogen: Recombinant Human Unconventional myosin-Ig protein (209-389AA)
other info2 :
Conjugate: Non-conjugated. Buffer: Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. Species: Human. Research Area: Signal Transduction
products description :
Unconventional myosin required during immune response for detection of rare antigen-presenting cells by regulating T-cell migration. Unconventional myosins are actin-based motor molecules with ATPase activity and serve in intracellular movements. Acts as a regulator of T-cell migration by generating membrane tension, enforcing cell-intrinsic meandering search, thereby enhancing detection of rare antigens during lymph-node surveillance, enabling pathogen eradication. Also required in B-cells, where it regulates different membrane/cytoskeleton-dependent processes. Involved in Fc-gamma receptor (Fc-gamma-R) phagocytosis.
ncbi gi num :
239582755
ncbi acc num :
NP_149043.2
ncbi gb acc num :
NM_033054.2
uniprot acc num :
B0I1T2
ncbi summary :
MYO1G is a plasma membrane-associated class I myosin (see MIM 601478) that is abundant in T and B lymphocytes and mast cells (Pierce et al., 2001 [PubMed 11544309]; Patino-Lopez et al., 2010 [PubMed 20071333]).[supplied by OMIM, Jun 2010]
uniprot summary :
MYO1G: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. 4 isoforms of the human protein are produced by alternative splicing. Protein type: Contractile; Motor. Chromosomal Location of Human Ortholog: 7p13. Cellular Component: membrane; phagocytic cup; plasma membrane. Molecular Function: phosphatidylinositol-3,4,5-triphosphate binding; phosphatidylinositol-3,4-bisphosphate binding; phosphatidylinositol-4,5-bisphosphate binding. Biological Process: T cell mediated immunity
size1 :
0.05 mg
price1 :
160 USD
size2 :
0.1 mg
price2 :
235
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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